ID R6EX18_9FIRM Unreviewed; 932 AA.
AC R6EX18;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=BN538_00329 {ECO:0000313|EMBL:CDB01336.1};
OS Lachnospiraceae bacterium CAG:215.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1262985 {ECO:0000313|EMBL:CDB01336.1, ECO:0000313|Proteomes:UP000018007};
RN [1] {ECO:0000313|EMBL:CDB01336.1, ECO:0000313|Proteomes:UP000018007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:215 {ECO:0000313|Proteomes:UP000018007};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB01336.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBCV010000404; CDB01336.1; -; Genomic_DNA.
DR AlphaFoldDB; R6EX18; -.
DR Proteomes; UP000018007; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF6; ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 135..316
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 326..423
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 428..771
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 773..846
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 932 AA; 106035 MW; A6CCD014C3A9E378 CRC64;
MKLYDLRTEY KVNPIGITEK NPRFSWKLES DVNDTMQQSY HIVVKEKDRI VWEAKEESED
SVLIAYAGEE LKDETCYDVT VEVTDNHGHT ATGEMSFETG ILEPETFQAK MITHDFPEDE
TACPIFSRTF TAKGKVKKAR IYATSRGVYE AYLNGERIGA DRMTPGWTSY HHRLQYQIYD
ITEMIREENE IEIMVGNGWY KGIFGFMLTP NIYGDRVGAF AEIHLEYEDG SREAICTDES
WNIRTGAVRY SEIYMGETID TTIGRDSDRA DTACVGSACE SSVCADSGVR TGTVSAMEFD
KQTLTAQENE PVRITERIPA KELIVTPKGE KLVDFGQNLT GLVELKVHGR KGQKIVIRHA
EVLDKDGNFY TETLRQAKSE DTYICNGEEQ VFLPHFTFHG FRYICVEGMD DLNLDQFTAC
VMHSDMEKTG DFHCSNQKVN QLQSNIAWGQ RGNFLDIPTD CPQRDERLGW TGDAQIFSWT
ASFNRNTALF FRKWMRDVAA ESSLEKGVPH VVPDILGQYS SSAWSDVAVI VPWVVYQTYG
DKGILEENWK CMHEWVDYIK NQCGENGLWQ TGYQYGDWLA LDKEESADRT GATDKYMIAN
AYYLYVTDLV RQTAEILGFA EEERTYRKLY DTTLEAFRQE YYTNTGRIVS ETQTGAILSL
YFHLAREKDR KRILQTLKTN IENHKNHLAT GFVGTPYLCH TLSENGEHEL AATIFMKEDY
PSWLYAVNMG ATTIWERWNS IMPDGSFDVS GMNSLNHYAY GSIGDWMYRK VAGVSQLKPG
YKKFKVQPMF VKGIEESGVE FESVYGKIES KWSCKDGKIC GYVNVPVNTT AEIHLPEKED
VLTVGSGVYK YEYETTTNLA YERFSLDSTF GEIMSQPLAV ELFEQMAPGV LDNPMLAMAQ
QMTLSEVLSV ASEARPLYEA VVNALNAAER QG
//
