ID   R6G5H8_9CLOT            Unreviewed;       331 AA.
AC   R6G5H8;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN   ORFNames=BN542_01772 {ECO:0000313|EMBL:CDB16591.1};
OS   Clostridium sp. CAG:221.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262780 {ECO:0000313|EMBL:CDB16591.1, ECO:0000313|Proteomes:UP000018176};
RN   [1] {ECO:0000313|EMBL:CDB16591.1, ECO:0000313|Proteomes:UP000018176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:221 {ECO:0000313|Proteomes:UP000018176};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB16591.1}.
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DR   EMBL; CBDC010000108; CDB16591.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6G5H8; -.
DR   Proteomes; UP000018176; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06259; YdcF-like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR003848; DUF218.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   PANTHER; PTHR30336:SF18; MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF02698; DUF218; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          162..308
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
SQ   SEQUENCE   331 AA;  37644 MW;  D607FCEB76749C45 CRC64;
     MGILISFCCI FTLVTVLAMI IEPSRFRNGI LILFCIAFWC LALLGHFFKN PDSWTTFLIV
     TLIMMVPICY GLITLFLFIN GIIVILREGF SFSHSLSLIL SLIMFTLPIG LVLFIISNMH
     NGRINILLCA LTLIFYFMIS FGGYFCYSLV YSIIPRRLKC NYIIIHGAGL LPDGTMTPLL
     KRRVDKALAI YYKCKKKPKI VVSGGKGSDE KISEAEAMAN YLFSKGIARN QVILEKKSTN
     TYENLKFSKE ILDEIENHGY YKCIFVTNNY HVLRTAFYAR KLNLHAKGVG CHTAGYYLPS
     AFIREYLAVM KMNTKSLVVL VFLLVLELFL I
//