ID   R6HXK0_9FIRM            Unreviewed;       236 AA.
AC   R6HXK0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Sialidase domain-containing protein {ECO:0000259|Pfam:PF13088};
GN   ORFNames=BN517_01791 {ECO:0000313|EMBL:CDB41770.1};
OS   Ruminococcus sp. CAG:177.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262952 {ECO:0000313|EMBL:CDB41770.1, ECO:0000313|Proteomes:UP000018315};
RN   [1] {ECO:0000313|EMBL:CDB41770.1, ECO:0000313|Proteomes:UP000018315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:177 {ECO:0000313|Proteomes:UP000018315};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB41770.1}.
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DR   EMBL; CBDQ010000055; CDB41770.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6HXK0; -.
DR   STRING; 1262952.BN517_01791; -.
DR   Proteomes; UP000018315; Unassembled WGS sequence.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR43752; BNR/ASP-BOX REPEAT FAMILY PROTEIN; 1.
DR   PANTHER; PTHR43752:SF2; BNR_ASP-BOX REPEAT FAMILY PROTEIN; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018315};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..236
FT                   /note="Sialidase domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004408136"
FT   DOMAIN          149..236
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
FT   REGION          22..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..69
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        80..110
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   236 AA;  24721 MW;  D7675794A8B9A998 CRC64;
     MKRFLALAIA VLMILSFAAC ASDKSGSDGS DTTAASDIKT DAATAPAADD TTAAPETTEP
     ATSGTDAVSA APSVRRGPTK TTPAADTTKP ASGDNSGSTT VPSKPDDSKP SAVETNPKKI
     IVSAEKEWIF TKKPTDSCHA STVLPLDNGT VVAAWFAGSS ESDDDVKILT SVRGTDGKWG
     EPIRVSADPN VAHWNPVLFQ NDDGTITLYF KVGKDTEYWK TYYSVSTDGK NWAAPR
//