ID R6HY23_9FIRM Unreviewed; 677 AA.
AC R6HY23;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Sulfatase family protein {ECO:0000313|EMBL:CDB42798.1};
GN ORFNames=BN517_00982 {ECO:0000313|EMBL:CDB42798.1};
OS Ruminococcus sp. CAG:177.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262952 {ECO:0000313|EMBL:CDB42798.1, ECO:0000313|Proteomes:UP000018315};
RN [1] {ECO:0000313|EMBL:CDB42798.1, ECO:0000313|Proteomes:UP000018315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:177 {ECO:0000313|Proteomes:UP000018315};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB42798.1}.
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DR EMBL; CBDQ010000145; CDB42798.1; -; Genomic_DNA.
DR AlphaFoldDB; R6HY23; -.
DR STRING; 1262952.BN517_00982; -.
DR Proteomes; UP000018315; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:UniProt.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693:SF33; ARYLSULFATASE; 1.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018315};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 203..527
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 677 AA; 75719 MW; 0E722A712D400191 CRC64;
MKKKIEFDSG KKVFPIIVSV IGTALMLAMW ITRLNMTAVI CVGFCCIVSA LIVIGMFFKR
RLYLGFLIGY CAALFGVITY YIVFGADAGF GAFTSGLAGF SSAEHSWLTG EGNFFTRLLG
NLLLALPSIA VIVGVILCVV KIDKKVTLQK VLSRVLSVLL VFTTVAFVLT MNLRSKPNAE
RLWDGQDDYL KGIDKNKTKE NSPNVLFILM DDLGYGDVSA NGAIYDTPNI DRIGEEGAQF
TNFYSSYSVC SPARFAALTG RYPYRGYADN VIYPTVDTFS PFASTRIFNS VEMGGNADGM
LGDEITIAEA LKGAGYATGC FGKWHLGDYG EYLPTNQGFD YFYGSHYVND MNPFYHVREE
NGEYEIARGT DELKDQSNAT KWIYEEINSW ITDQVKQGDE PFFAFYATPW PHAPVYVGDE
FKGKSGMGTY VDCVTEFDYY LGKLFDTLEE LGVMDNTIIV FTSDNGPALQ GSTGDLRGGK
YLAYEGGQKV PFMIRWGNNG GLFKAGSTYD ESATLVDLFP TLIEMCGVTG NGGTQKNYLP
ADRVIDGVSM VPVFTQNKVI HTAETPILHM KREKLKAIQY AIPTADILSH EEYKDYDFDV
LKNNEYVVFK YFKNIQNDNS AFFDKFRKNW LHILTDDAGE NYNRTPAYPT IADEMRDRLD
EKMNEFKNNR RGIIENS
//
