ID R6IT67_9CLOT Unreviewed; 819 AA.
AC R6IT67;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Negative regulator of genetic competence ClpC/MecB {ECO:0000313|EMBL:CDB52480.1};
GN ORFNames=BN539_00095 {ECO:0000313|EMBL:CDB52480.1};
OS Clostridium sp. CAG:217.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262779 {ECO:0000313|EMBL:CDB52480.1, ECO:0000313|Proteomes:UP000018364};
RN [1] {ECO:0000313|EMBL:CDB52480.1, ECO:0000313|Proteomes:UP000018364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:217 {ECO:0000313|Proteomes:UP000018364};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB52480.1}.
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DR EMBL; CBDU010000149; CDB52480.1; -; Genomic_DNA.
DR AlphaFoldDB; R6IT67; -.
DR STRING; 1262779.BN539_00095; -.
DR Proteomes; UP000018364; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS50151; UVR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018364};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 4..148
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 418..453
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 142..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 414..460
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 149..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 819 AA; 90766 MW; CE5D8DF9991B5BAA CRC64;
MYRFNYFTEK ANHVINLAIT SAEELGHNYI GSEHLLLGIL KEDAGLGAQA LRESGVQTED
VEKLIKENIG VGEPTRLTPD DFTPRFKRML ELAFQIARGM MHSFVGTEHL LLALLKETDS
YGYKFLLALG VRPEVLVEQL FSGQETQPDG KTDGKKGKTK TPTLDEFGRD LTALAEGGKI
DPVIGREKEI ERVIQILSRR SKNNPCLIGE PGVGKTAIAE GLALKIVKHE VPELLEGKKI
VALDLTSMVA GTKYRGDFEE RIQKAMDEVK QAGNIILFID EVHTLMGAGS AEGATDAANI
LKPALARGEI QVIGATTIDE YRKNIEKDAA LERRFQPVTV GEPTEEQTVE ILKGLRDKYE
AHHKVKITDA AIENAVKMSS RYIADRFQPD KAIDLIDEAC SKVRLAAYTA PPNLKEMETE
IKRLAAEKTA AVRSQNFEQA AELRDKEKSL QDLLDQEKEK WKNTSSHDVK EVTPADIAAV
VSGWTGIPVQ QITKEESQRL LQLEKILHQR IVGQDKAVSA VARAIRRGRA GLKNPKRPMG
SFIFLGPTGV GKTELCKTLA EAMFGDENAI IKLDMSEYME KHTVSKLIGA PPGYVGFDEG
GQLTEKVRRK PYCVVLFDEI EKAHPDVFNM LLQILEDGVL TDSQGRKVSF KHAVIIMTSN
VGASKITDSR QALGFGDDKD AAKTIEDLVM EELKKTFKPE FLNRVDEIVV FNQLEKQDIQ
EIARRMLKAL NKRLADLDVQ ATFTDAAVDA LADKGFDKVY GARPLRRAIQ TQIEDPLSEL
LLEDKIHGTV TVDYKDGAFT FDSPADKDKQ EQPAAPAAD
//
