ID   R6K0M4_9FIRM            Unreviewed;       918 AA.
AC   R6K0M4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Pyridine nucleotide-disulfide oxidoreductase {ECO:0000313|EMBL:CDB66985.1};
GN   ORFNames=BN561_00830 {ECO:0000313|EMBL:CDB66985.1};
OS   Eubacterium sp. CAG:248.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1262885 {ECO:0000313|EMBL:CDB66985.1, ECO:0000313|Proteomes:UP000018194};
RN   [1] {ECO:0000313|EMBL:CDB66985.1, ECO:0000313|Proteomes:UP000018194}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:248 {ECO:0000313|Proteomes:UP000018194};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB66985.1}.
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DR   EMBL; CBDZ010000183; CDB66985.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6K0M4; -.
DR   Proteomes; UP000018194; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.70.20; -; 1.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   PANTHER; PTHR43100:SF2; FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE, CHLOROPLASTIC-LIKE; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF00037; Fer4; 2.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 2.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 2.
DR   PROSITE; PS51379; 4FE4S_FER_2; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018194}.
FT   DOMAIN          304..333
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
FT   DOMAIN          853..882
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   918 AA;  101768 MW;  57DF81D34AFD7F8C CRC64;
     MSKEEFKNPH PELPVREPVL RLGKMITDRV PIKLGFEKLT ADSPEYWGLA PICTDEQAEI
     ALKMGVRKPK TLKQMVKITG MDEKELEKQL EQMSFNGLLE YNWENPEHEK QYVLPMFVPG
     SAEFTNMNST VLEEHPEMGR FFERMSRLPL EKITPMVPPG GAGIGMHVIP VEKAIDMNNQ
     AVSLEKISYW LDKYDGKYAA SPCSCRKSRK TYDEGCADDP ADWCIAVGDM ADYVVETGKG
     GRYITKEEAL EIFKKAEDNG FVHQITNIDG QDKIFAICNC NVNVCYALRT SQLFNTPNMS
     RSAYVAEVTK ENCVACGRCV EYCPAGAVKL GQKLCTKAGE EVKYPKMPLP SEQKWGPHMW
     SEDYRDKNRI NCYDTGTAPC KTACPAHIAV QGYLKMAAQG RFIDALALIK KENPFPAVCG
     HVCNRRCEDA CTRGTIDEAI AIDEVKKFIA MQDLKADTRY IPKKVVPSTK GSFDEKVAII
     GGGPAGLSCA FYLAEKGYKP TVFEKNEKAG GMLVYGIPSF KLEKDVVEAE IDVIHKMGVD
     IKTGVEVGKD ITIDELKKQG YKAFYIAIGC QGSRKAGIPG EDADGVVSAV DFLKQAGYTH
     EYPLEGDVVV IGGGNVAIDV ARTSTRVGDY NVSMFCLEDR KGMPASEEEV EEALEEGVKL
     DCGWGPKEIL TEDGHVTGIV LKRCISVKDA DGRFNPQYDE NDLKTINCRH VFLSIGQSTI
     WGELLKGTKV QVDGVRVKAD KLTYQTTDPD IFIGGDVYTG PRFAIDAIAA GKEAAISIHR
     YVQPHSSLTI GRNRREFIEL DKNNISIESY DNSSRQVPGT DTSFNHKKSF KDAKLTFTEE
     QVKKETARCL GCGASVVDPN KCIGCGICTT KCEFDAIHLN RELPECSTMR KSEDKLKYIL
     PYGAKQAIKI KFAGKKNK
//