ID R6KDK2_9FIRM Unreviewed; 566 AA.
AC R6KDK2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Lysine decarboxylase {ECO:0000313|EMBL:CDB68116.1};
GN ORFNames=BN564_00178 {ECO:0000313|EMBL:CDB68116.1};
OS Eubacterium sp. CAG:252.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262887 {ECO:0000313|EMBL:CDB68116.1, ECO:0000313|Proteomes:UP000017970};
RN [1] {ECO:0000313|EMBL:CDB68116.1, ECO:0000313|Proteomes:UP000017970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:252 {ECO:0000313|Proteomes:UP000017970};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-I family.
CC {ECO:0000256|ARBA:ARBA00010671}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB68116.1}.
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DR EMBL; CBEA010000090; CDB68116.1; -; Genomic_DNA.
DR AlphaFoldDB; R6KDK2; -.
DR Proteomes; UP000017970; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000310; Orn/Lys/Arg_deCO2ase_major_dom.
DR InterPro; IPR008286; Prn/Lys/Arg_de-COase_C.
DR InterPro; IPR036633; Prn/Lys/Arg_de-COase_C_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR PANTHER; PTHR43277; ARGININE DECARBOXYLASE; 1.
DR PANTHER; PTHR43277:SF3; LYSINE DECARBOXYLASE; 1.
DR Pfam; PF01276; OKR_DC_1; 1.
DR Pfam; PF03711; OKR_DC_1_C; 1.
DR SUPFAM; SSF55904; Ornithine decarboxylase C-terminal domain; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 7..314
FT /note="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P
FT attachment site"
FT /evidence="ECO:0000259|Pfam:PF01276"
FT DOMAIN 478..540
FT /note="Orn/Lys/Arg decarboxylase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03711"
SQ SEQUENCE 566 AA; 63835 MW; 6867FABE368F707A CRC64;
MKDNYKYKDM ISHLREYSEK NVVPMHMPGA KRNNRLINEY MPDIGNPYEI DITEIDGFDN
MHNAEGIIKA AFDRTARLYG ADESLFLVNG STAGNMAAIC GVTNKGDCII AARNCHVSVY
NAIIQNELEV EYVYPQYDEK YGYYKGITLE EIKEAVEKHL LVSENIKAVV ITSPTYEGNV
SDIKSIAEYL HSYNIPLIVD EAHGAHFRFS EEFPATAVEC GADIVINSVH KTLPSLTQTA
VMHINYGYVN VEKVRRYWNI YQSTSPSYIL MGSIDRCMSI IEKDGKPLFD NYIRRLKELR
GRLKQLKNIK LIESDDISKI VLGYRSGKEL YEVLLKRYGI QLEMSSLKYV IAMTSIFDEQ
SNYDRLYNAL REIDEDDNQD KCMSDEKACV SDGCVSEGSM QNDGNSENRV SGNLMLNDIL
KDNSIHNSSV AVTYNSADII ENNNIEKDRN NKNNAYNKCN NYDKDISEVN IAGFNNKCAM
KISEALNIGD ECGYDTVSMD SDDVYGRISA AMVYVYPPGI PILCPGEVVS ENVVDIIKQA
VEEGIEVVGL EEAGNEIRKR SILCLR
//
