ID R6KGT4_9BACE Unreviewed; 806 AA.
AC R6KGT4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BN506_03759 {ECO:0000313|EMBL:CDB72655.1};
OS Bacteroides cellulosilyticus CAG:158.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1263038 {ECO:0000313|EMBL:CDB72655.1, ECO:0000313|Proteomes:UP000018191};
RN [1] {ECO:0000313|EMBL:CDB72655.1, ECO:0000313|Proteomes:UP000018191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:158 {ECO:0000313|Proteomes:UP000018191};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB72655.1}.
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DR EMBL; CBEB010000327; CDB72655.1; -; Genomic_DNA.
DR AlphaFoldDB; R6KGT4; -.
DR Proteomes; UP000018191; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000018191}.
FT DOMAIN 320..357
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 526..579
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 597..806
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 806 AA; 93717 MW; 65CA23D87252AD4F CRC64;
MKEKPNIDCE KYRQIAQMAK MGWWESDLKN RQYICSDFII DLLGLESDRI SFEDFHERIR
EDHRRRLRNE YFSLTNIETY EQMFPIRAKD GDIWVYSKIS FKQPDEEGYK NMIGYLQCID
KQTGETSENA DSLQVNSLLY QQNSLSYSLL AFLQSDDITQ IINKILADLL KQTKGDRTYI
FEIDREHKIQ SCIYEATAEG ISQELDFLQD VPWDDSLWWD RQISEKRSII LNTLDDMPPE
AKVYRDTLEV QDIKSVMVVP LLSKDKVWGY MGIDMVRTHR SWSNIDHQWF SSLGNIISIC
LQLRKAELQA KEDRRALDHS EKILRNIYKN LPVGIELYDK DGYLVDMNDK ELEIFGLADM
KEALGVSLFE NPNIPEDVKE KLRARENVDF SINYDFSKID RYVTSRRKDV INLQTKVALL
YDSQNQFSNY LFINIDTTET TSAYTKIQEF EHLFLLIGDY AKVGFAHFNI MTRDGYAQNT
WYRNLGEKEN TPMPQVIGVY SHVHPEDCAV LKQFVGQVKE GKATSLSKEV RINRGNGKYS
WTSINVMVRD YRPQDGVIEM LCINYDITPL KETEQKLIIA RDKAEELDRL KSAFLANMSH
EIRTPLNSIV GFSSLLAETD DREERQEYIK IVETNNELLL QLVSDILDLS KIESGTFDFV
RSDLDVNESC MKIIKSMEMK VPETVDLVFE KYMPDCHIYT DKNRFMQVIT NFINNALKFT
KQGTIALGYE QTAPHEIKFY VRDTGFGIPK EKIDSIFERF VKLNTFVQGT GLGLSICKSL
VSQMGGKIGV ESTEGEGSCF WFTHPY
//
