ID   R6L9X0_9BACE            Unreviewed;       512 AA.
AC   R6L9X0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Tat (Twin-arginine translocation) pathway signal sequence {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN506_02400 {ECO:0000313|EMBL:CDB71037.1};
OS   Bacteroides cellulosilyticus CAG:158.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1263038 {ECO:0000313|EMBL:CDB71037.1, ECO:0000313|Proteomes:UP000018191};
RN   [1] {ECO:0000313|EMBL:CDB71037.1, ECO:0000313|Proteomes:UP000018191}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:158 {ECO:0000313|Proteomes:UP000018191};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family.
CC       {ECO:0000256|ARBA:ARBA00005836}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB71037.1}.
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DR   EMBL; CBEB010000167; CDB71037.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6L9X0; -.
DR   Proteomes; UP000018191; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR   InterPro; IPR025502; TldD.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR   PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR   Pfam; PF01523; PmbA_TldD_1st; 1.
DR   Pfam; PF19290; PmbA_TldD_2nd; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   PIRSF; PIRSF004919; TldD; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018191};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..512
FT                   /note="Tat (Twin-arginine translocation) pathway signal
FT                   sequence"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004411912"
FT   DOMAIN          71..135
FT                   /note="Metalloprotease TldD/E N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01523"
FT   DOMAIN          161..268
FT                   /note="Metalloprotease TldD/E central"
FT                   /evidence="ECO:0000259|Pfam:PF19290"
FT   DOMAIN          277..510
FT                   /note="Metalloprotease TldD/E C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19289"
SQ   SEQUENCE   512 AA;  55998 MW;  ECA02E1D82CA3F21 CRC64;
     MDRRNFLRMG SLAVLGSLAA PSLALPDTVR GALGGTDNKS AVAAAMKHFG VTEADLKKVL
     TAALEKGGDY ADLYFEHSFN NAVALMDGKV NNCSSNIDFG MGVRVLAGDQ SGYAYVEGVT
     LEEMLRAART AARIASSGKA GKPVAFKEKT IDRDRYSVVT PWEEVSLKEK MPYLQKLNDK
     VFALDNRVRK VQASLSDNTT HVLFCNSEGV TYYDYRPMVS YMAFCIMEEN GRMENNYATR
     SYRKGFEFMT DDIIEVIARE VVDNTAIMFK AIKPKGGELP VVMASGGSGI LLHEAIGHAF
     EADFNRKNVS IFADQLNKKV CNEHISVVDD GTIPFNRGSV NFDDEGIEGQ KTYIVKDGVL
     TSYLHDRISS KHYGVAPTGN GRRDTFRNVP IPRMRATYME AGDMKEEDII STVKNGIYAQ
     QFTNGQVQIG AGDFTFFVKF GYMIEDGKLT QPIKDINIIG NGPKALADIT MVASNDQIDN
     GTWTCGKDGQ SCPVTCGMPS ALVSKLTVGG EN
//