ID R6M1M2_9FIRM Unreviewed; 736 AA.
AC R6M1M2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=BN515_00418 {ECO:0000313|EMBL:CDB88326.1};
OS Firmicutes bacterium CAG:170.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1263006 {ECO:0000313|EMBL:CDB88326.1, ECO:0000313|Proteomes:UP000018279};
RN [1] {ECO:0000313|EMBL:CDB88326.1, ECO:0000313|Proteomes:UP000018279}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:170 {ECO:0000313|Proteomes:UP000018279};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB88326.1}.
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DR EMBL; CBEH010000322; CDB88326.1; -; Genomic_DNA.
DR AlphaFoldDB; R6M1M2; -.
DR Proteomes; UP000018279; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF5; CELLULOSE-BINDING SDE182 NUCLEOSIDE HYDROLASE-LIKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000018279}.
FT DOMAIN 35..169
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 197..296
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 301..638
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 642..702
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 736 AA; 82519 MW; 3F7C8E8A059E6AC0 CRC64;
MSQILEYASW IYPSEDIGEI CPVFRKHFTA RPGAAAKLEI TAFGVYEAFL NGQRIGNFFL
APGWTSYPTR LQVQTYDLTA LLREENELTV TLGKGWFAGR ISAGVYQAIA DGPRLLAALH
LTDADGTREY ATNESWQWAE SPIRFSDIYD GETYDARVTP ENWRFCRTDS CGKQMLIPQE
GEIVTEHERL KPVAVLHTPK GEMVLDFGQE ITGYAEFTVQ ARAGERVLLS CAEVLDADGN
FYTENYRSAK SRIEYICRDG IQTGRAHHTF YGFRYLRVDE APEGWQAENF TAVCVYSDLQ
RTGWIRTSDP LLNQLYQNIV WGEKDNLLDV PTDCPQRDER LGWTGDAQVS IRAITCTFDG
KRFFSKWLRD MAAEQRGDGT VSHFVPNVGL FTKDPALFCG GSAWADAAVI CPWQLYQAYG
DKELLREHLP MMQKWVEYVC RAAGDSCIWS TGHHYGDWLA LDAGEGNYTG ASRKEFIATA
FYAHSAQLLA QAMDALDMDG AAYHRLFETI RAAHQNAFPD CRTQTECALA LHFGLAAAPD
RVAAQLAELV RSNGNRLTTG FVGTPYLLHA LSENGYAQTA YDLLLQTKAP SWLFSVKMGA
TTVWEHWDSR KADGSFWSTD MNSFNHHAYG AVADWLYGAA GGIRPGKPGY ETVLFSPIPN
RRLQRFEVVV NTPHGKVCSC WKWNGPTVTY VLTTPVSAEI RLGGEQHNVA AGTYTFVRGG
YDKSPYEAKD FLNVRR
//
