ID R6M7X3_9CLOT Unreviewed; 703 AA.
AC R6M7X3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Chaperone ClpB 2 {ECO:0000313|EMBL:CDB92004.1};
GN ORFNames=BN595_00844 {ECO:0000313|EMBL:CDB92004.1};
OS Clostridium sp. CAG:302.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262793 {ECO:0000313|EMBL:CDB92004.1, ECO:0000313|Proteomes:UP000018278};
RN [1] {ECO:0000313|EMBL:CDB92004.1, ECO:0000313|Proteomes:UP000018278}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:302 {ECO:0000313|Proteomes:UP000018278};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB92004.1}.
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DR EMBL; CBEJ010000040; CDB92004.1; -; Genomic_DNA.
DR AlphaFoldDB; R6M7X3; -.
DR STRING; 1262793.BN595_00844; -.
DR Proteomes; UP000018278; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000018278}.
FT DOMAIN 52..196
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 449..614
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 613..702
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT COILED 259..346
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 703 AA; 79668 MW; 0A95BAFDE52C6959 CRC64;
MNMNNPYEEN LQKPLEKYGR DITKAAKDGK IDPVIGRDEE IRSITRILSR KTKNNPVLIG
EPGVGKTAIV EGLAQRIIKG DVPNNLKDKT IWELDMGALV AGAKYRGEFE ERLKAVLKEV
KDSEGNIIMF IDEIHMIVGA GALEGAMDAG NMLKPMLARG EVHCIGATTL NEYRKYIEKD
AALERRFQKV LVKEPTVLDT ITILRGLKSK FEVFHGVTIK DKALIAAATL SDRYITDRFL
PDKAIDLVDE AAATIKVQME SVPTALDNLE RNIMRLEIEK EALKKEKDNI SKNRITEIDK
ELDNLKLKEK DLKTKWEEEK TVNTKISKKK EEIDRANFEL ETAENNYDLE SAARLRHGTI
PKLEKELASL EEINKSEILS DTVDEESIAA IISKWTNIPV SKLAEGDKEK LLHLEDKMKE
RVKGQDNAIH LVTEAIIRSR AGIKDPNRPI GSFIFLGPTG VGKTEVARTL AYELFDDERH
MIRIDMSEYM ESHSVARLIG APPGYVGYDE GGQLTEAVRR NPYSIVLFDE IEKAHHDVFN
VLLQILDDGR ITDGQGRTVD FKNTIIIMTS NLGSEYILDN KDNANELVMQ ELRSTFKPEF
INRIDEIIIF NSLTKDVVYD ILNKIIKDIE YRLRDKNIKI NVTDKAKEFI VNASYDEKYG
ARPIKRYVQR NVETLIAEAI INDKISFGST ITIDVDSDKL ILK
//
