GenomeNet

Database: UniProt
Entry: R6M8I7_9CLOT
LinkDB: R6M8I7_9CLOT
Original site: R6M8I7_9CLOT 
ID   R6M8I7_9CLOT            Unreviewed;       293 AA.
AC   R6M8I7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   12-APR-2017, entry version 19.
DE   SubName: Full=Chromosomal replication initiator protein DnaA {ECO:0000313|EMBL:CDB92259.1};
GN   ORFNames=BN595_01035 {ECO:0000313|EMBL:CDB92259.1};
OS   Clostridium sp. CAG:302.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium; environmental samples.
OX   NCBI_TaxID=1262793 {ECO:0000313|EMBL:CDB92259.1, ECO:0000313|Proteomes:UP000018278};
RN   [1] {ECO:0000313|EMBL:CDB92259.1, ECO:0000313|Proteomes:UP000018278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:302 {ECO:0000313|Proteomes:UP000018278};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDB92259.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CBEJ010000044; CDB92259.1; -; Genomic_DNA.
DR   Proteomes; UP000018278; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018278};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018278}.
FT   DOMAIN      203    272       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   293 AA;  34072 MW;  D24067355FF26001 CRC64;
     MHAIGNYILE NSNKKVLYVS SEQFVNDYIY AVRNNEKNSF DRIDSFKNKY RNIDVLIIDD
     IQFLGSATKG QEEFFHTFNE LHDSNKQIII ASDRSVDDLK MLENRLITRF NWGLTANITP
     PDFNLRVDII KKKISHQEAA EDIPIEVIEY IANINDSDVR QLEGAITRVF AYASMMNRGI
     INLDIAIEAL KDKVSEKSVY KNDVHRIQRI VCEYFKIDIE DLKGKKRSKD VNYPRQIAIY
     LCRKMTSESF PKMGTYFGGR DHSTIISAYQ KIENDLKTNP QLQIVINELK EKI
//
DBGET integrated database retrieval system