ID   R6MAE2_9CLOT            Unreviewed;       618 AA.
AC   R6MAE2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II {ECO:0000313|EMBL:CDB91356.1};
GN   ORFNames=BN595_00021 {ECO:0000313|EMBL:CDB91356.1};
OS   Clostridium sp. CAG:302.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262793 {ECO:0000313|EMBL:CDB91356.1, ECO:0000313|Proteomes:UP000018278};
RN   [1] {ECO:0000313|EMBL:CDB91356.1, ECO:0000313|Proteomes:UP000018278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:302 {ECO:0000313|Proteomes:UP000018278};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB91356.1}.
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DR   EMBL; CBEJ010000012; CDB91356.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6MAE2; -.
DR   STRING; 1262793.BN595_00021; -.
DR   Proteomes; UP000018278; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR   PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:CDB91356.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018278}.
FT   DOMAIN          44..428
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
SQ   SEQUENCE   618 AA;  69945 MW;  2B9D4C7EF59C9D09 CRC64;
     MSLIENIEEI KKEIRTNPSN SFDIIKNNVP KYTMYQYVRE CNKNNLNNFA FRFGRKRYTY
     GEFIELIDRY AKGFIGMGIG KGDRVALLLP NLPESTIIIY ALNKIGAISD NIDPTSKEDR
     MKYFLEKEKI KAIVCFDKVY ETGVKPIEEY IYNELNIDKV LITKITDSLP LIESALYKMK
     CKDEDVVKNV STLYSGINIL NVNRFLRESR YQLSYTNPYT ENEIATICHS SGTTGIPKTI
     PSSNENVNFI AFQHQISDVD YSNVKTFLHV LPGFAQFGFS DSMHLGHSLG LEMIEIPIFS
     QENIIDILLD TKANCLFGSP SFWLRLIGDD RYKDADLSFL YEAVYGGGSL TITQVANINR
     FLVAHNAKCL LRTGYGMSEF NGTCILEDPF MSTPGSCGFD LPGGSGIIIN PDTMKEVSTG
     ESGNLYYSKG SNPICEFDGK VLHEVLNING REYIDTGDIM RKNARGEYFF EGRASGMICR
     YDGYKVYPCV LENAITSSPF IEDAMVSEYY DKTKFGAMPL IYVILSKNSK AIDIKSIISS
     IIDNYILSNK NMSFRDIPTK WKVVDELPYT TALKKDYKKI KDDGINGSEI SIVCHETNMG
     LDYYDVIVPN KNKTLIKK
//