ID R6MAJ5_9CLOT Unreviewed; 742 AA.
AC R6MAJ5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=DNA segregation ATPase FtsK/SpoIIIE protein-like protein {ECO:0000313|EMBL:CDB91396.1};
GN ORFNames=BN595_00259 {ECO:0000313|EMBL:CDB91396.1};
OS Clostridium sp. CAG:302.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262793 {ECO:0000313|EMBL:CDB91396.1, ECO:0000313|Proteomes:UP000018278};
RN [1] {ECO:0000313|EMBL:CDB91396.1, ECO:0000313|Proteomes:UP000018278}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:302 {ECO:0000313|Proteomes:UP000018278};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDB91396.1}.
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DR EMBL; CBEJ010000014; CDB91396.1; -; Genomic_DNA.
DR AlphaFoldDB; R6MAJ5; -.
DR STRING; 1262793.BN595_00259; -.
DR Proteomes; UP000018278; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000018278};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 398..590
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 200..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 650..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 416..423
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 742 AA; 82152 MW; 316205D44A9C1A3D CRC64;
MAKKKTKKDS EKKKFEYTNE VVGIILILAA IIGIGAYGPA GNFIKSFAVF LVGNIYPFLL
FGLLILGGYL IVKRKTPNLL SLRWIGFYIL VISFLVLLHL KYIEVHSQEG IKIITETFNN
LLKAFDNTGN TNIVDTISYA ISNSGGGMIG AIFTYAFFSL FKDGTKIVII TLIVIGTILL
FNTSLIDLIK KIKVPKIKKK EHKEKENADT TDSRIILPTV DKTPDKEEKD LPVESDIPIK
TASASVMVKE DTEEEKPVIN VNYKLPPLTL LKLSKGNNDK ENIEAVKQNI TTLEKVLADF
EIPGKIKECH IGPSVTQYEL ELKAGTKVNK LLSIQKEIAL NLAAKDVRIQ APIPGKSTIG
IELPNKVNSA VSFREILSKL PEPSDKSLLA VGLGKDIMGT VKWAEINATP HLLIAGATGS
GKSVCINCII ASILMRTKPD EVKLVMVDPK KVELSMYNGV PHLLTPVVTD PKKASIALKN
IVVEMERRYQ VFEDTKCKNI SSYNKMCETN TDYVKMPYIV FIIDELADLM LVAAKDVEDS
IMRITQMARA AGIHLIVATQ RPSTDVITGV VKANIPSRIS FAVSSSIDSR TILDQTGAEK
LLGKGDMLFK PMGENVPIRI QGAYVSDEEL QKIVDFTISQ QKANYDHSIT EERGGEGTDA
GKYDDGYESK EEYDDPLYND IVDFAMEFGK ISASLIQRKY RIGYNRAARI VDLLEERGII
GPQNGSKPRE VLARKEVNTE EE
//
