ID   R6MFY4_9BACE            Unreviewed;      1398 AA.
AC   R6MFY4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Putative CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:CDB98528.1};
GN   ORFNames=BN659_02540 {ECO:0000313|EMBL:CDB98528.1};
OS   Bacteroides sp. CAG:443.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262739 {ECO:0000313|EMBL:CDB98528.1, ECO:0000313|Proteomes:UP000018098};
RN   [1] {ECO:0000313|EMBL:CDB98528.1, ECO:0000313|Proteomes:UP000018098}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:443 {ECO:0000313|Proteomes:UP000018098};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB98528.1}.
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DR   EMBL; CBEN010000059; CDB98528.1; -; Genomic_DNA.
DR   Proteomes; UP000018098; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 2.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 2.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014}.
FT   DOMAIN          4..256
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          322..579
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          670..882
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
SQ   SEQUENCE   1398 AA;  154946 MW;  1B8EBE3EDA947FD2 CRC64;
     MFKVGIDIGS TTVKIVVLGE EKKLLFSRYK RHNARAKAVV AETLKELLIE KGDIEVSVCV
     TGSVGLGMSE QYAFPFVQEV VAATQAIRQD YPSVASMIDI GGEDAKIVFF KHGEPADLRM
     NGNCAGGTGA FIDQMAVILG TTVDQLNELA LKATQIYPIA SRCGVFCKTD IQNLVAKNVS
     REDIAASIFH AVAVQTVVTL AHGWDIKSPI LFCGGPLTFI PALRKAFMEY LHLSEGDVIL
     PENGALLPAT GAALSAHADC RIYRLSDLIT KLTAETSTAY NQCSGLMPIF SGQKSYEEWQ
     KQISKNKLGR ASLKPGVQDV YIGIDSGSTT TKIVVTDSDD NILFTYYKPN GGHAIETVAE
     GLNLLKEQCL KTQTTLNIKG SCSTGYGEDL IKAAFQLDAG IVETIAHYVA AHYLDKDVSF
     ILDIGGQDMK AIFVNDGIID RIEINEACSS GCGSFIETFA NTLGYTAHDF SQAACRSSKP
     CDLGSRCTVF MNSKVKQVLR EGATVDDIAA GLAYSVVKNC LYKVLKLKDV SELGKHIVVQ
     GGTMRNDAVV RALEQLTGAQ VIRCDMPELM GAFGCAIYAR EHCNTSVSLD EIVSQAHYST
     HLLHCKGCDN QCQVFRYRFD NGKNYYSGNR CEKVFTNGSK EQPGENIYRF KNELLFGRSK
     TVPEKPRMVI GIPRSLNMYE NFPFWHTLLT ACGIEVRLSG ESTYAGYEQS ARMVMSDNIC
     FPAKLVHGHV QNLIAQKVDR IFLPFVIFER KGKEQNSYNC PVVTGYSEVV KSVQSSGIPI
     DSPAISFKDE DLLYKQCSNY LKSLGVEESQ IKEAFAKATE VQEDYAASLV AHNKQVLENA
     RQQNHMVVLL AGRPYHTDML IQHKISDVLA DMGIDVISDD IVRENGQKIE NVHFLAQWSY
     PNRILEAAQW CAAQGDDVQF VELTSFGCGP DAFLVDEVRD VLIRNGKTFT LLKLDDINNV
     GSMKLRIRSL IESMKLFHEH RAGRKEQNTA VAVSECKDHY KNKKILVPYF TPFISPLIPA
     IMRLAGYDVE NLALSNAESC EWGLKYANNE VCYPATLIVG DVVKAFKSGR YNPEETVVAM
     TQTGGQCRAS NYVSLIKKAL EEAGYPHTPV VSLTFGSSLE NKQPGLKVNW IKILPVALRA
     ILYSDCISKF YYAAAAREKE VGQAARLRDD FLQQAEGLIR DKRSKDLLDL LSVAAEQFNA
     ICRDMNCPKV GVVGEIFLKF NPFAQKNVIG WLTEKGIEVV PSVLTDFFMQ NFVNRKVRVE
     SCIQKSAMPD FVYKSAYKII NKQIGKFNKA GMKFRYFIPF KDIFEEAADA RKVISLNAQF
     GEGWLLPAEI MSYARQGIFN VVSLQPFGCI ANHIVSKGVE KRIKYFFPEM NILSLDFDSG
     VSDVNITNRL LLFVDHLK
//