ID R6NDN2_9CLOT Unreviewed; 582 AA.
AC R6NDN2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=NADH:ubiquinone oxidoreductase NADH-binding 51 kDa subunit {ECO:0000313|EMBL:CDC10288.1};
GN ORFNames=BN649_01685 {ECO:0000313|EMBL:CDC10288.1};
OS Clostridium sp. CAG:413.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262803 {ECO:0000313|EMBL:CDC10288.1, ECO:0000313|Proteomes:UP000018076};
RN [1] {ECO:0000313|EMBL:CDC10288.1, ECO:0000313|Proteomes:UP000018076}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:413 {ECO:0000313|Proteomes:UP000018076};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC10288.1}.
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DR EMBL; CBES010000059; CDC10288.1; -; Genomic_DNA.
DR AlphaFoldDB; R6NDN2; -.
DR STRING; 1262803.BN649_01685; -.
DR Proteomes; UP000018076; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018076};
KW Ubiquinone {ECO:0000313|EMBL:CDC10288.1}.
FT DOMAIN 525..554
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 555..582
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 582 AA; 62738 MW; 16200CA218620257 CRC64;
MYKIKIGEGS CGISAGAGKI HKLLDEKSNG NYTVRTVGCI GMCFLEPIVD IYDGDTLIAR
LVKVSPDDID KIISFTESGD MSQINSLVIS NDDRSFLEKQ TRIALRGCGI TEPESIEDYE
KHGGYTALSK VLKTMAPEQV IEEIKTSGLA GRGGAGFPTW FKWNAARQSA GDEKYLICNA
DEGDPGAFMD RAVIESDPHA LIEGMLIAAY AIGAKEAIVY VRAEYPLAIK RLRNAIEQAE
EKGYIGENIL SSGFSCRFRI KAGAGAFVCG EETALIESLE GQRGMPRLKP PFPAQSGYMN
KPSNINNVET FANVTWIINN GGEAFAAIGT ETSKGTKVFA LTGKIKRGGL VEIPMGKTLR
DVVFDIGGGI RGDKEFKGVQ LGGPSGGCIP AQLADTVIDY KALSATGAIM GSGGMVVMDE
STCMVRMAKF FLDFTTNESC GKCVPCRIGT MRLRETLERI CQGSGRDGDI KLLEELCAQI
KDGSLCGLGQ TAPNPVLTTL RYFRDEYEAH IKEHRCPAGE CPELISYHID SDKCRGCTLC
SKKCPVGAIS GEVKKPHKID SGKCIKCGSC KAACRFDAIF IK
//
