ID   R6NQJ0_9BACE            Unreviewed;       938 AA.
AC   R6NQJ0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Peptidase M16 inactive domain protein {ECO:0000313|EMBL:CDB99942.1};
GN   ORFNames=BN659_00717 {ECO:0000313|EMBL:CDB99942.1};
OS   Bacteroides sp. CAG:443.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262739 {ECO:0000313|EMBL:CDB99942.1, ECO:0000313|Proteomes:UP000018098};
RN   [1] {ECO:0000313|EMBL:CDB99942.1, ECO:0000313|Proteomes:UP000018098}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:443 {ECO:0000313|Proteomes:UP000018098};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDB99942.1}.
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DR   EMBL; CBEN010000097; CDB99942.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6NQJ0; -.
DR   Proteomes; UP000018098; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670}; Signal {ECO:0000256|SAM:SignalP};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..938
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004427337"
FT   DOMAIN          54..169
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          209..392
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          692..868
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   938 AA;  106130 MW;  2F5A347039564BAA CRC64;
     MRSFIKKTFA AIILIGGTVS VCAQQMPPLP TDPNVRIGKL DNGLTYYIRH NALPEKQADF
     YIAQKVGSIL EEDNQRGLAH FLEHMCFNGT TNFPGNTLRE YLESIGVKFG TNLNAYTAID
     ETVYNIDNVP VIRDGIIDSC LLILHDWADD LTLDPKEIDK ERGVIHEEWR TRTGAMMRMY
     DTVFPKMFAG SKYAYRLPIG SMDIVDHFPY QDLRDYYEKW YRPDLQGIIV VGDIDVDQIE
     AKIKKIFGPI KMPQNAAERK YFPVPDNKEP IIAIAKDKEQ QMNQVYVYHK HDPFPEEMKN
     TVGYLVYNYM TGAISSMLNT RLQELTQTAT PPFINAGVED NDFVLAKTKK AFMGVAICKD
     DGIATGLSAL MREIERARQF GFTEGEYTRM KADYLRAIEN AYNERDKMKS NQFVNQYVSN
     FINGDPIPSI EDEYALMTQI VPNIPLDNVN KLLQSLVTDS NTVVSLFCPD KPEVKLPTEA
     DIKKILADVK AEKLEPYVDK VSNEPLMKEA PTGGKVVKTE KGPFGSTVLT LNNGVRVIMK
     STNFKADEIR MSSFSRGGTS LFDEKDALQF KQINDVAGLG GLGNFSVVDL QKVLSGKVAS
     AGASVNTLTE SVTGKCSPKD LETMLQLTYL SFTAPRMDST AFESYKNRLK AQLANMEVNP
     NIALSDTLRK ELYGDNPRVL RIKADMVDKT DYQKIMDMYK DRFKDASDFT FIFVGNLDQA
     TATPLIEKYL GSLPSINRKE DFRDVNLDIR KGEHKNVFHR DLQTQKATVC IIRSGECEYT
     LKNQLMMSML SQLLTMEYTE TVREDEGASY GVGVSGDISL YPKVEATLQI SFDTNPEKRA
     KMSSLIDKGI NDFIANGPKA ENLKKVKEYM LKNYEANQKE NGYWINILYS YYWENTDMAT
     KYVDTVNQIT SADLQKFAKD FFSQDNRIEV SMTSGDTK
//