ID R6QXG5_9FIRM Unreviewed; 643 AA.
AC R6QXG5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=BN606_00061 {ECO:0000313|EMBL:CDC37654.1};
OS Butyrivibrio sp. CAG:318.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio; environmental samples.
OX NCBI_TaxID=1262761 {ECO:0000313|EMBL:CDC37654.1, ECO:0000313|Proteomes:UP000018075};
RN [1] {ECO:0000313|EMBL:CDC37654.1, ECO:0000313|Proteomes:UP000018075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:318 {ECO:0000313|Proteomes:UP000018075};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC37654.1}.
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DR EMBL; CBFF010000034; CDC37654.1; -; Genomic_DNA.
DR AlphaFoldDB; R6QXG5; -.
DR STRING; 1262761.BN606_00061; -.
DR Proteomes; UP000018075; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:CDC37654.1};
KW Cilium {ECO:0000313|EMBL:CDC37654.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:CDC37654.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018075};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..106
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 369..632
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 258..316
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 643 AA; 70292 MW; B81C2DAE284B1283 CRC64;
MAIRLTGLNS GLDTDAMVKE LVSAYSTKKD KYVKAKTKHE WKMSAWKNTN TKVYSFYTST
LSKMRYSSGY NLRSASISDT TIATVKAASG ATASTQSLEV TRLATSGYLT GGKVTDTNGA
KVSANTKLSE LGITDGTLKI NDTFVTLDGD TTLSGLASKL KGTDVSVNFD ATSQRFFVSS
SKSGAEGEFT LTAGDEAGIA ALQKLGLYSA ADVNGDESAE VAYYKKMASA NADDVISSRY
EKAKYTTESY TKYIEGLAKS AKSNKESAES KLKEITADDY KWEDDYKTEE EYNKAKDELN
DKITKYTKEL DDNNALLADS SKLAVSMDEA NAKIKDSITK QVNGEIAAAQ KIVNEGIYTN
SADSARIVAQ DAEIKLNGAT FTGSTNSFSI NGLTIDAKNT TQSAVTITTS VDTQGIYDKI
KELLKGYNEM IGNIDEQYYA ESAKGYEPLT NDEKEAMTDK QIEEWEDKIK KALLRKDGTL
GGISSALKNV FYSTSIEKDG VKYNIASFGI ATGGYFTTEQ KDRGKFHIDG DPDDSLTSTN
SDKLMAAIAN DPDTVMEYFQ TLSQNLYDAL SDKMSATPLS SAFTIYNDKE MSSQYSDYKK
KVSEWEEKLK DIEDSYYKKF AKMESALSKL QSQTSQLSSL FGN
//
