ID R6UGY5_9CLOT Unreviewed; 454 AA.
AC R6UGY5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Penicillin-binding protein transpeptidase domain protein {ECO:0000313|EMBL:CDC79441.1};
GN ORFNames=BN818_00673 {ECO:0000313|EMBL:CDC79441.1};
OS Clostridium sp. CAG:964.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262848 {ECO:0000313|EMBL:CDC79441.1, ECO:0000313|Proteomes:UP000018136};
RN [1] {ECO:0000313|EMBL:CDC79441.1, ECO:0000313|Proteomes:UP000018136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:964 {ECO:0000313|Proteomes:UP000018136};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDC79441.1}.
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DR EMBL; CBFZ010000039; CDC79441.1; -; Genomic_DNA.
DR AlphaFoldDB; R6UGY5; -.
DR STRING; 1262848.BN818_00673; -.
DR Proteomes; UP000018136; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018136};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 150..445
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 454 AA; 48334 MW; 4E82BD1E20D11976 CRC64;
MRKTRSRSTM VLIIALLAIV GLCVFIVKIF LNAGQWIQHS YNGHLAGSGG LSSAGEIFDR
SGNTLAYSQD GERLYNSDYT TRLSTLHVVG DDSLNISSAI QSSYRSQLIG FNYLWGLGLP
SSLKAGGNIT LTIDSSACNA AYNALDGHNG AVVVYNYKTG EVLCSVSTPT YDPMDPPEIT
EDNEKEYDGV YVDKVLAGLY APGSTFKIIT AAAALENIPD IENETFTCNG STNIGGNEIT
CMHIHGELTM KEGLAQSCNV VFSELAARLG KDKMTAMAEK LGFNSSVIVN STETARQVYN
VSKADENGLG WSGIGQYTVE ANPMQMAIMC GAIANGGTAV LPNEIKSGVM EINGGTKDMM
DSDLAAKLDE YMRYDVTSYY GDSLFPSLTV CAKTGTAEVG ENKEPHAWMV GYSQDEDAPL
AFAVIVENGG YGFSTAGPVA VAAMEACASV LRSE
//
