ID   R6WBE4_9FIRM            Unreviewed;       344 AA.
AC   R6WBE4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Kinase PfkB family {ECO:0000313|EMBL:CDC91507.1};
GN   ORFNames=BN546_01146 {ECO:0000313|EMBL:CDC91507.1};
OS   Firmicutes bacterium CAG:227.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263010 {ECO:0000313|EMBL:CDC91507.1, ECO:0000313|Proteomes:UP000018294};
RN   [1] {ECO:0000313|EMBL:CDC91507.1, ECO:0000313|Proteomes:UP000018294}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:227 {ECO:0000313|Proteomes:UP000018294};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000256|ARBA:ARBA00010688}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDC91507.1}.
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DR   EMBL; CBGC010000049; CDC91507.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6WBE4; -.
DR   STRING; 1263010.BN546_01146; -.
DR   Proteomes; UP000018294; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01166; KdgK; 1.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   Gene3D; 2.20.150.10; putative 5-dehydro-2- deoxygluconokinase; 1.
DR   InterPro; IPR030830; Myo_inos_IolC.
DR   InterPro; IPR023314; Myo_inos_IolC-like_sf.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR029056; Ribokinase-like.
DR   NCBIfam; TIGR04382; myo_inos_iolC_N; 1.
DR   PANTHER; PTHR43085:SF49; 5-DEHYDRO-2-DEOXYGLUCONOKINASE; 1.
DR   PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR   Pfam; PF00294; PfkB; 1.
DR   SUPFAM; SSF53613; Ribokinase-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000313|EMBL:CDC91507.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018294};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          14..321
FT                   /note="Carbohydrate kinase PfkB"
FT                   /evidence="ECO:0000259|Pfam:PF00294"
SQ   SEQUENCE   344 AA;  38397 MW;  4077DA06DA1A5467 CRC64;
     MKYVEFDETR PMDLVLLGRV AIDFNPAYND QVKEEFKPLK KVHMFEKFVG GSPANIAVGV
     TRHGLKAGFF AKVSDDQFGE FVVDYFNEQG IDTSRISKCT NGEKLGLTFT EMLSPKESSI
     LMYRNCIADL QLSVDDIDEE YIKQTKAILI SGTALAESPS REAAIKAVML AKKNNTKVIF
     DIDYREYNWK NSDEISIYYS IVAKEADIIM GSREEFDLTE KLIQPGMSDE ESAALWQGYN
     AKIVVIKHGM KGSTAYTCDG QKFSIKPFPV QARKGFGGGD GYGSGFLYGL YQGWQVIDCL
     EFGSAEASMM VRSNNCSDSL PGPDAVHAFI KEEKEQYGEM IARV
//