ID R6Y705_9BACE Unreviewed; 459 AA.
AC R6Y705;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Glycoside hydrolase family 29 (Alpha-L-fucosidase) {ECO:0000313|EMBL:CDD31748.1};
GN ORFNames=BN762_01923 {ECO:0000313|EMBL:CDD31748.1};
OS Bacteroides sp. CAG:714.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1262749 {ECO:0000313|EMBL:CDD31748.1, ECO:0000313|Proteomes:UP000018068};
RN [1] {ECO:0000313|EMBL:CDD31748.1, ECO:0000313|Proteomes:UP000018068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:714 {ECO:0000313|Proteomes:UP000018068};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD31748.1}.
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DR EMBL; CBGW010000020; CDD31748.1; -; Genomic_DNA.
DR AlphaFoldDB; R6Y705; -.
DR Proteomes; UP000018068; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CDD31748.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018068};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..459
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004425138"
FT SITE 299
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 459 AA; 53347 MW; 13899DB4CADFFEB0 CRC64;
MRKFKQFAAC LMGLALSMGV YAQDDANSFV HEQSDGYEWP TDQAVLKKLD QWQDLKFGVL
FHWGLYSVPG ICESWPLCSE DWITRPIDSY YDYKRWYWGF SEKFNPTDFN PDQWADIMQA
AGMKYMIFTT KHHDGFCMFD SKYTDFSIAK GPFANNPKKD VARYVFDAFR QKEFMIGCYF
SKPDWHCKWF WHPYYDTAGR MQNYKRERHP DWWKNYQDFT YNQLMELTSN YGKFDILWLD
GGWVTGDEVR LDEVLAHART HGHEGLISVD RTIKGKNENY QTPERSIPEK QLDHPWESCI
TLSHSWGWVP DVKFKSPNEV LALLAEITAK GGCLLLGVGP TPQGLIQPEV ETCLRQVGKW
LKKNGQAIYN TRITPDYNDG NTWFTADKDG KTLYAVYTVK DGEEMPATIE WKGNVPTGTM
KLLNKNVSVR YQCDGDKVKV TLPKGLANEP LAFRFTVKK
//
