ID R6YB99_9FIRM Unreviewed; 828 AA.
AC R6YB99;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Negative regulator of genetic competence ClpC/MecB {ECO:0000313|EMBL:CDD31185.1};
GN ORFNames=BN815_02329 {ECO:0000313|EMBL:CDD31185.1};
OS Firmicutes bacterium CAG:94.
OC Bacteria; Bacillota.
OX NCBI_TaxID=1262989 {ECO:0000313|EMBL:CDD31185.1, ECO:0000313|Proteomes:UP000018237};
RN [1] {ECO:0000313|EMBL:CDD31185.1, ECO:0000313|Proteomes:UP000018237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:94 {ECO:0000313|Proteomes:UP000018237};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD31185.1}.
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DR EMBL; CBGU010000382; CDD31185.1; -; Genomic_DNA.
DR AlphaFoldDB; R6YB99; -.
DR Proteomes; UP000018237; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000018237};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 5..147
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 425..460
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 421..474
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 828 AA; 91429 MW; 6D1935339BCF2EF8 CRC64;
MTYRFNGFTE KANNAMNLAI SSAEELGHDY VGSEHVMLGL LKEGSGVAYT VLNKLGVTAE
AYEKLIRERI GTGEPTSLSP DEFTPRTKRI LQVAAVAGAQ LHNAYVGTEH LLIAIIEDGQ
SYAMRFLQIL GADPNRIVAE LSNMLNNTGF HKQNEARPGG GEEGGQTGKA LEQFGRDLTQ
LAAQGKIDPV IGRQNEIERV IQILCRRTKN NPVLIGEPGV GKTAVAEGLA LKIQAGEVPE
LLKNKRLVSL DLTGMVAGTK YRGDFEERIK SAIDEVKQDG NVILFIDELH TIIGAGSAEG
SADAANILKP ALARGDFQVI GATTINEYRK HIEKDAALER RFQPVMVGEP SEDEAVEILK
GLKDRYEAHH KVTITDEAID AAVKLSARYI ADRYLPDKAI DLIDEAASRV RLRTFTAPDD
LQELEKKIKD MEIDKAAAVN AQDFERAASL RDKEKELQDQ LERAKDEWAS KNERSNSVVV
PTDIADIVSM WTGVPVSQLT EEESKRLLRL EDTLHQRVIG QEEAVSAIAK AIRRGRVGLK
DKNRPIGSFI FLGPTGVGKT ELCKALAEAM FGDEKAMIRF DMSEYMEKHT VSRLVGSPPG
YVGFDEGGQL TEAVRTKPYS VVLFDEIEKA HPDVFNILLQ ILEDGRVTDS QGKTVDFKNT
VIIMTSNVGA RLITEKQQSL GFNQASSEEA AQEADFEKTK ELVMGELKAL FRPEFLNRVD
DIIVFHKLTK EDTQKIARKM LATLEKKLHD MDIQMEFTDA AVEAVADKGY DPTYGARPLR
RVIQNQVEDP ISEKMLEGAI TANKAYRCDY TEGKFTFEPA EAAAPAAE
//
