ID R6YTS2_9FIRM Unreviewed; 445 AA.
AC R6YTS2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Transglutaminase-like predicted protease domain fused ChW-repeats and cell-adhesion domain {ECO:0000313|EMBL:CDD34804.1};
GN ORFNames=BN600_01106 {ECO:0000313|EMBL:CDD34804.1};
OS Roseburia sp. CAG:309.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262945 {ECO:0000313|EMBL:CDD34804.1, ECO:0000313|Proteomes:UP000018292};
RN [1] {ECO:0000313|EMBL:CDD34804.1, ECO:0000313|Proteomes:UP000018292}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:309 {ECO:0000313|Proteomes:UP000018292};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDD34804.1}.
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DR EMBL; CBGX010000107; CDD34804.1; -; Genomic_DNA.
DR AlphaFoldDB; R6YTS2; -.
DR STRING; 1262945.BN600_01106; -.
DR Proteomes; UP000018292; Unassembled WGS sequence.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.10.620.30; -; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR003343; Big_2.
DR InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR PANTHER; PTHR46333; CYTOKINESIS PROTEIN 3; 1.
DR PANTHER; PTHR46333:SF2; TRANSGLUTAMINASE-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02368; Big_2; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR SMART; SM00635; BID_2; 1.
DR SMART; SM00460; TGc; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDD34804.1};
KW Protease {ECO:0000313|EMBL:CDD34804.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018292};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..445
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004426314"
FT DOMAIN 223..296
FT /note="BIG2"
FT /evidence="ECO:0000259|SMART:SM00635"
FT DOMAIN 357..413
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|SMART:SM00460"
SQ SEQUENCE 445 AA; 49527 MW; 33F42E6062CF82D5 CRC64;
MKKGICKLIL FCALLVLTGL IPERQTNAAE EYTYYITFNQ IYQYEITKEQ FESIRGNWNS
LTPEGVLEIA RQIVPEDQIP SHLTNIGIRA VPKNSSEGEL PAYPSDKTEN LVPDNGFVVS
QGVLLRYEGK EEVVTIPDTV TSIYQGAFMQ NAAVKKVIIP SSVKNISNAA FYQCPNLQFI
VCAGKAASVG EYMVYQCESI VNMVAPKSSK EYAYAKGHDI PVVTSEKTVL EAKTLHLLKG
DKQTVKLYNA LGTIRWKSSA PAVVSVDARG KLLAKRAGKA KITAQFGGKK YTLTVQVQTK
SEDKRVDQVI KTVIKKGMSA REKVKAVHNW LIRNVKYDYH NYLRGTVPHV SHTSKGALVR
GLAVCDGYSK AFMKIMKKLK IPCKMIAGVS EGGGHAWNLV KVGGKWLHVD VTFDDPIVNG
KNTNTRPRYT YFLKTDAQMR KDHAW
//
