ID   R6ZPJ7_9FIRM            Unreviewed;       459 AA.
AC   R6ZPJ7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Glutamate synthase (NADPH) homotetrameric {ECO:0000313|EMBL:CDD50428.1};
GN   ORFNames=BN599_00982 {ECO:0000313|EMBL:CDD50428.1};
OS   Firmicutes bacterium CAG:308.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263016 {ECO:0000313|EMBL:CDD50428.1, ECO:0000313|Proteomes:UP000017945};
RN   [1] {ECO:0000313|EMBL:CDD50428.1, ECO:0000313|Proteomes:UP000017945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:308 {ECO:0000313|Proteomes:UP000017945};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD50428.1}.
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DR   EMBL; CBHE010000046; CDD50428.1; -; Genomic_DNA.
DR   AlphaFoldDB; R6ZPJ7; -.
DR   Proteomes; UP000017945; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR028261; DPD_II.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006004; SudA-like.
DR   NCBIfam; TIGR01316; gltA; 1.
DR   PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR   Pfam; PF14691; Fer4_20; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00419; ADXRDTASE.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017945}.
FT   DOMAIN          19..129
FT                   /note="Dihydroprymidine dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF14691"
FT   DOMAIN          142..446
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   459 AA;  50087 MW;  C78927F2439AE192 CRC64;
     MPNMSLEKIA MPVQPADERI KNFEEVATGY TAEMAMEEAT RCLHCKHKPC VNGCPVNVNI
     PDFIEKVKDG EFEEAYRIIS LTSSLPAVCG RVCPQENQCE KYCVRGIKGE SVAIGRLERF
     VADYHRENND APLTKPESNH HKVAIVGAGP AGLTCAGDLA KQGYEVTIFE ALHVAGGVLM
     YGIPEFRLPK EIVQKEISHL KELGVEIVTN FVVGRSDSID SLIESGYEAI FIGSGAGLPN
     FMNLEGENLK GVYSANEFLT RINLMKAYKE GSATPVQHPK KCVVVGGGNV AMDAARCARR
     LGSEVHIVYR RSMEELPARK EEVEHAQEEG IIFDLLCNPV KVLGDENGWV NGIECVRMEL
     GEPDESGRRR PVEIKDSNFT IDIDCMIMAI GTSPNPLIRH TTEGLEVNRK GCFIVDDKNM
     TSRAGIYAGG DAVTGAATVI QAMGAGKKAA SSIHEYLSK
//