ID   R7A784_9FIRM            Unreviewed;       318 AA.
AC   R7A784;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Zn-dependent proteases {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN599_01400 {ECO:0000313|EMBL:CDD51369.1};
OS   Firmicutes bacterium CAG:308.
OC   Bacteria; Bacillota.
OX   NCBI_TaxID=1263016 {ECO:0000313|EMBL:CDD51369.1, ECO:0000313|Proteomes:UP000017945};
RN   [1] {ECO:0000313|EMBL:CDD51369.1, ECO:0000313|Proteomes:UP000017945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:308 {ECO:0000313|Proteomes:UP000017945};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase U62 family.
CC       {ECO:0000256|ARBA:ARBA00005836}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD51369.1}.
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DR   EMBL; CBHE010000081; CDD51369.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7A784; -.
DR   Proteomes; UP000017945; Unassembled WGS sequence.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR   InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR   InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR   InterPro; IPR035068; TldD/PmbA_N.
DR   InterPro; IPR036059; TldD/PmbA_sf.
DR   PANTHER; PTHR30624:SF4; METALLOPROTEASE TLDD; 1.
DR   PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR   Pfam; PF19290; PmbA_TldD_2nd; 1.
DR   Pfam; PF19289; PmbA_TldD_3rd; 1.
DR   SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017945}.
FT   DOMAIN          5..75
FT                   /note="Metalloprotease TldD/E central"
FT                   /evidence="ECO:0000259|Pfam:PF19290"
FT   DOMAIN          82..314
FT                   /note="Metalloprotease TldD/E C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19289"
SQ   SEQUENCE   318 AA;  34173 MW;  17FF7216B7B997CE CRC64;
     MLNVKQHVQI SNSNGKLVQD TRIRTRMPVT AYAQDEKSMQ SGFEGPGASM GLEFYDTTQP
     EDIAKEAARI ALVMLEAKDC PSGKMPVVID NGFGGVIFHE ACGHALEASA VSKDQSVFTN
     KLNTKIASDC VTAIDDGTIP NAWGSQNVDD EGNPQQKRVL IKDGELTSYM IDTLNGRRMN
     MASTGSSRRQ SYKYEPTSRM SNTYIAAGKD KFEDLFKGIK KGLYAKKMGG GSVNPQTGEF
     NFAVNEGYMI IDGKITYPVK GASLIGNGAE ILMNIDKVSD NLKRAQGMCG ASSGNIPTDV
     GQPAIRVSSI TVGGTVNE
//