ID   R7CXA0_9BACE            Unreviewed;       810 AA.
AC   R7CXA0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Alpha-glucosidase {ECO:0000313|EMBL:CDD82058.1};
GN   ORFNames=BN666_01475 {ECO:0000313|EMBL:CDD82058.1};
OS   Bacteroides sp. CAG:462.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1262740 {ECO:0000313|EMBL:CDD82058.1, ECO:0000313|Proteomes:UP000018063};
RN   [1] {ECO:0000313|EMBL:CDD82058.1, ECO:0000313|Proteomes:UP000018063}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:462 {ECO:0000313|Proteomes:UP000018063};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC       {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDD82058.1}.
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DR   EMBL; CBHU010000055; CDD82058.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7CXA0; -.
DR   STRING; 1262740.BN666_01475; -.
DR   Proteomes; UP000018063; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd14752; GH31_N; 1.
DR   CDD; cd06591; GH31_xylosidase_XylS; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR   InterPro; IPR033403; DUF5110.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR048395; Glyco_hydro_31_C.
DR   InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR   InterPro; IPR000322; Glyco_hydro_31_TIM.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR43863; HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G03140)-RELATED; 1.
DR   PANTHER; PTHR43863:SF2; MALTASE-GLUCOAMYLASE, INTESTINAL-LIKE; 1.
DR   Pfam; PF17137; DUF5110; 1.
DR   Pfam; PF13802; Gal_mutarotas_2; 1.
DR   Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR   Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361185};
KW   Hydrolase {ECO:0000256|RuleBase:RU361185};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018063};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..810
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004442367"
FT   DOMAIN          36..196
FT                   /note="Glycoside hydrolase family 31 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13802"
FT   DOMAIN          238..591
FT                   /note="Glycoside hydrolase family 31 TIM barrel"
FT                   /evidence="ECO:0000259|Pfam:PF01055"
FT   DOMAIN          601..707
FT                   /note="Glycosyl hydrolase family 31 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21365"
FT   DOMAIN          724..790
FT                   /note="DUF5110"
FT                   /evidence="ECO:0000259|Pfam:PF17137"
SQ   SEQUENCE   810 AA;  93859 MW;  FB1D4A53277AE394 CRC64;
     MKLRNICFLL VWLCAVLPLQ ARTDKAITRQ VGDVNIVLQF YTPSIVRVVK YPAADRQPDK
     QSYSVILKPD AGKVTSAEDN GRLTLSTHDL QVQLDLSTGI VGFYTASGNL LMQEKACSFT
     KRHGDNDEGK YRLSQTWQVA PDELLYGLGQ LRDTCMVQRG RHVDIWNHNT YISIPYITSE
     KGWGLYWDNP GKSYYDDNGE GTTFTSEVGL CSDYYFIYRD GTQDGVIASI RELTGQATLF
     PLWTMGYWQC RERYKTSDEL AEVLDNYRRL QIPLDGIVQD WQYWGCDSNW NAMRFMNPYY
     INKVGDPAWD KYLPNDMRTL TPKQPRLKSP SEMVDYVHGN HAHLMITIWP DFGPWTEPYA
     ELKEIDALLP FDTWPRNAGV LVADVFNPKA RDIYWKHLTN LYRMGFDAWW TDSTEPDHFE
     KPGDDDYMTH DGTWRSVKNA FSLVHNRGIY EHQRAMKGNT KRSVQMTRSG AFGLQHYGTF
     SWSGDILASW QEMKQQVPSG LNYSLCGIPF WNTDLGGFFY WEFEQDPKNP ALQELQTRWM
     EWGTFMPLMR NHCSSPMVSE LYLFGKEGDW AYDAMKKFIR LRYRLLPYIY SNAGAAVQHS
     NTLMRALVMD YAHDRKAATR NDEYLFGRNL LVKPVTDPMY TWKDDNKRGH LIYPDVKQAA
     APVEVYLPEG NDWYDFWTNE RLNGGQTLRR PCPIDIMPVY VKAGSILPWG PDVQYSSEKP
     WDDLEIRVYP GADGTFTLYE DEGDNYNYEK GAFTEITFNW KDATRELTIG TRQGAFKGML
     KNRRFHIVVM EENGATRQAD YDGTLLRLSL
//