GenomeNet

Database: UniProt
Entry: R7FBU6_9FIRM
LinkDB: R7FBU6_9FIRM
Original site: R7FBU6_9FIRM 
ID   R7FBU6_9FIRM            Unreviewed;       876 AA.
AC   R7FBU6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   22-NOV-2017, entry version 19.
DE   RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE            EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN   ORFNames=BN611_01573 {ECO:0000313|EMBL:CDE12310.1};
OS   Ruminococcus sp. CAG:330.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae;
OC   Ruminococcus; environmental samples.
OX   NCBI_TaxID=1262954 {ECO:0000313|EMBL:CDE12310.1, ECO:0000313|Proteomes:UP000018377};
RN   [1] {ECO:0000313|EMBL:CDE12310.1, ECO:0000313|Proteomes:UP000018377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:330 {ECO:0000313|Proteomes:UP000018377};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Endohydrolysis of (1->4)-beta-D-glucosidic
CC       linkages in cellulose, lichenin and cereal beta-D-glucans.
CC       {ECO:0000256|RuleBase:RU361166}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E)
CC       family. {ECO:0000256|RuleBase:RU361166}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDE12310.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CBIH010000080; CDE12310.1; -; Genomic_DNA.
DR   Proteomes; UP000018377; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd02850; E_set_Cellulase_N; 1.
DR   Gene3D; 2.60.120.260; -; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase-like.
DR   InterPro; IPR004197; Cellulase_Ig-like.
DR   InterPro; IPR003305; CenC_carb-bd.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR001701; Glyco_hydro_9.
DR   InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   Pfam; PF02018; CBM_4_9; 1.
DR   Pfam; PF02927; CelD_N; 1.
DR   Pfam; PF00759; Glyco_hydro_9; 1.
DR   SUPFAM; SSF48208; SSF48208; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS00698; GLYCOSYL_HYDROL_F9_2; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU361166};
KW   Cellulose degradation {ECO:0000256|RuleBase:RU361166};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018377};
KW   Glycosidase {ECO:0000256|RuleBase:RU361166};
KW   Hydrolase {ECO:0000256|RuleBase:RU361166};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Polysaccharide degradation {ECO:0000256|RuleBase:RU361166};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018377};
KW   Signal {ECO:0000256|RuleBase:RU361166};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     30       {ECO:0000256|RuleBase:RU361166}.
FT   CHAIN        31    876       Endoglucanase. {ECO:0000256|RuleBase:
FT                                RU361166}.
FT                                /FTId=PRO_5005145682.
FT   TRANSMEM    844    868       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       33    176       CBM-cenC. {ECO:0000259|Pfam:PF02018}.
FT   DOMAIN      211    289       CelD_N. {ECO:0000259|Pfam:PF02927}.
SQ   SEQUENCE   876 AA;  95453 MW;  BF453D2B10BAA530 CRC64;
     MRQNRVLGVL TALTIAVTSG SALPALSVSA GQLLGQTDFE DGVGLPWHVC ESASGKMSFE
     VTDSAYRITV DNPGGASNGG EDRWDCQFRH RGLTLVSGCT YEVAYDITAS NNCTYYTKIG
     DMSEPFTEDW HGNPDDSQFD AFWNVQNLTA NQTVSFHGTF TAKRTAEVEW AFHVGGDTVS
     VGTVFTFDNM SLICTDNDEY DYVPTQEWQR ADIVTNQIGY FPDCRKQATL ISDETDAVDF
     SLCDESGKEV YTGASKPMGE DPDSGDSVHI LDFSEFKEAG TYTLQAGNAA SREFAIGGTE
     VYSGMLFDAL NYFYQNRSGI AIESQYITSG DAAALARSAG HSNDTARITT DWDDLQSNGG
     SQNVSGGWYD AGDHGKYVVN GGIALWMMQN QYERAVSRKT EDSYADDTMQ IPEQQNGYPD
     LLDEARWEME WMLKMIVQDG TYQGMAYHKV HDIKWTALGM APADDQEERI LKPPTTCATL
     NLAACAAQAA RLWEPYDADF AKECLTAAEN AYEAAKKHDD LYAPLDQSIG GGPYGDDCAD
     DEFYWAACEL YLTTGEKAYL KDLEKSDLAY TVPTTLSAGE DADTAGSFDW GNTAALGTLS
     FALHKDDLEK KVAKKVTNAI TDAADVHLGR EEQQGYGQPY AQSKLSYADD DTGYVWGSNS
     FVADNTVILA AAYDLTGEQN YLNGVISAMD YLLGRNPMDV SYITGYGSHA VQYPHHRYWA
     HQISEEYPMA PAGVLVGGPN SGMQDPWVQG SGWKKGEIAP AKCYLDNIEA WSVNECTINW
     NAPLAWLTAF VCDANGGIVA NTGSMASEQL DPSAGDSEES SQTSAGSNQQ NQANDSTEKS
     SSGAFPWTLV IVLGAILLGA IIVEVFIYKI VKLKKN
//
DBGET integrated database retrieval system