ID   R7G2K4_9PROT            Unreviewed;       303 AA.
AC   R7G2K4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Cell filamentation protein Fic {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN767_00092 {ECO:0000313|EMBL:CDE20217.1};
OS   Acidiphilium sp. CAG:727.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acidiphilium.
OX   NCBI_TaxID=1262689 {ECO:0000313|EMBL:CDE20217.1, ECO:0000313|Proteomes:UP000018053};
RN   [1] {ECO:0000313|EMBL:CDE20217.1, ECO:0000313|Proteomes:UP000018053}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:727 {ECO:0000313|Proteomes:UP000018053};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE20217.1}.
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DR   EMBL; CBIM010000113; CDE20217.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7G2K4; -.
DR   STRING; 1262689.BN767_00092; -.
DR   Proteomes; UP000018053; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.3290.10; Fido-like domain; 1.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR003812; Fido.
DR   InterPro; IPR036597; Fido-like_dom_sf.
DR   InterPro; IPR040198; Fido_containing.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   PANTHER; PTHR13504; FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145; 1.
DR   PANTHER; PTHR13504:SF38; PROTEIN ADENYLYLTRANSFERASE AQ_AA38-RELATED; 1.
DR   Pfam; PF02661; Fic; 1.
DR   Pfam; PF13443; HTH_26; 1.
DR   SUPFAM; SSF140931; Fic-like; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   PROSITE; PS51459; FIDO; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR640198-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018053}.
FT   DOMAIN          7..60
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50943"
FT   DOMAIN          151..297
FT                   /note="Fido"
FT                   /evidence="ECO:0000259|PROSITE:PS51459"
FT   ACT_SITE        231
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-1"
FT   BINDING         235..242
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT   BINDING         267..268
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT   BINDING         275
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-2"
FT   SITE            101
FT                   /note="Important for autoinhibition of adenylyltransferase
FT                   activity"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640198-3"
SQ   SEQUENCE   303 AA;  34849 MW;  49D3B8EE5EA91634 CRC64;
     MYSYKPLENK LKALDLTKSD LTTQLGISSR TVAKISKGEK IAKNVLVRIA DFLHCRPDDL
     FREVCDNHIL QILREEKEVK ISGGLYHELQ VRMTYNSNHI EGSKLTEDQT RLIFETRTID
     VGDGIPVDDI IETSNHFRAI DYVIDKALEP LSEDIIKHLH LLLKQGTNDS SLDWFAVGDY
     KKRANTVGGR ETCKPSEVHK AMDKLVTNFN SKSDITIDDI IELHADFEYI HPFQDGNGRV
     GRLIALKECL RFNIIPFIIE DSKKAFYYRG LANWNQEKGW LRDTCLDGQD TFKRILKVLD
     IHE
//