ID   R7GNP6_9FIRM            Unreviewed;       494 AA.
AC   R7GNP6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Threonine synthase {ECO:0000256|ARBA:ARBA00018679};
GN   ORFNames=BN591_01065 {ECO:0000313|EMBL:CDE28720.1};
OS   Catenibacterium sp. CAG:290.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Coprobacillaceae; Catenibacterium; environmental samples.
OX   NCBI_TaxID=1262767 {ECO:0000313|EMBL:CDE28720.1, ECO:0000313|Proteomes:UP000018308};
RN   [1] {ECO:0000313|EMBL:CDE28720.1, ECO:0000313|Proteomes:UP000018308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:290 {ECO:0000313|Proteomes:UP000018308};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|PIRSR:PIRSR604450-51};
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- SIMILARITY: Belongs to the threonine synthase family.
CC       {ECO:0000256|ARBA:ARBA00005517}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE28720.1}.
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DR   EMBL; CBIQ010000121; CDE28720.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7GNP6; -.
DR   STRING; 1262767.BN591_01065; -.
DR   Proteomes; UP000018308; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd01560; Thr-synth_2; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR029144; Thr_synth_N.
DR   InterPro; IPR037158; Thr_synth_N_sf.
DR   InterPro; IPR004450; Thr_synthase-like.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   NCBIfam; TIGR00260; thrC; 1.
DR   PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR   PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR   Pfam; PF14821; Thr_synth_N; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR604450-51};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018308}.
FT   DOMAIN          5..79
FT                   /note="Threonine synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14821"
FT   MOD_RES         111
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ   SEQUENCE   494 AA;  55039 MW;  9BE406BBB7C6FF54 CRC64;
     MEKLFKSTRG NQTPIDFYTS ILQGIASDGG LLVPDFDFEK KNLEDLLPLN YVDLATEIIG
     TFAPSDAKEA LHTACNQAYG EGLFCDEVVP VKKAGNVYVA ELYQGPTAAF KDMALSMLPR
     MMTLSLKKKG EEREVMILAA TSGDTGKAAL EGFKDVEGTC IKVFYPIDGV SAIQQQQMVT
     TTGKNVEIIG IRGNFDDAQS AVKKAFGSKE LKELCDEHHI FLSSANSINI GRLIPQIVYY
     FYSYLTLVKR NEIKLGEAVN FTVPSGNFGN CLAGWIAKNM GLPVNQFIVA SNKNNILTDF
     FTTGTYDARR EFYKTNAPAM DILVSSNLER LVWFMVNGDS EKVNKYMEEL KETGVYKVDD
     ETLARVQKEF KAGCLGEEDV LKVVHDCWNE NKYLLDTHTA VGYGVYEEYV KNTGDTTKTI
     LLSTASPYKF PESVYQALTG EEVDVYTAIE KLHDLTGMEI SYPLKGIKDR EILHKGVIDR
     DAILDTIAEK IKEY
//