ID   R7H2I7_9FIRM            Unreviewed;       617 AA.
AC   R7H2I7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Cellulase (Glycosyl hydrolase family 5) {ECO:0000313|EMBL:CDE33874.1};
GN   ORFNames=BN645_00339 {ECO:0000313|EMBL:CDE33874.1};
OS   Ruminococcus sp. CAG:403.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262958 {ECO:0000313|EMBL:CDE33874.1, ECO:0000313|Proteomes:UP000017925};
RN   [1] {ECO:0000313|EMBL:CDE33874.1, ECO:0000313|Proteomes:UP000017925}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:403 {ECO:0000313|Proteomes:UP000017925};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|RuleBase:RU361153}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE33874.1}.
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DR   EMBL; CBIS010000200; CDE33874.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7H2I7; -.
DR   STRING; 1262958.BN645_00339; -.
DR   Proteomes; UP000017925; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd14256; Dockerin_I; 1.
DR   Gene3D; 1.10.1330.10; Dockerin domain; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR002105; Dockerin_1_rpt.
DR   InterPro; IPR016134; Dockerin_dom.
DR   InterPro; IPR036439; Dockerin_dom_sf.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR018087; Glyco_hydro_5_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR31297:SF41; ENDOGLUCANASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G01830)-RELATED; 1.
DR   PANTHER; PTHR31297; GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   Pfam; PF00404; Dockerin_1; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF63446; Type I dockerin domain; 1.
DR   PROSITE; PS51766; DOCKERIN; 1.
DR   PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023326};
KW   Cellulose degradation {ECO:0000256|ARBA:ARBA00023001};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW   Hydrolase {ECO:0000256|RuleBase:RU361153, ECO:0000313|EMBL:CDE33874.1};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017925}.
FT   DOMAIN          549..617
FT                   /note="Dockerin"
FT                   /evidence="ECO:0000259|PROSITE:PS51766"
SQ   SEQUENCE   617 AA;  68364 MW;  26B94EC69700E568 CRC64;
     MKQSHTSHPY HRIQACLVAM LCLLTLLGAS ISQTISASAK ETTLTGQSAK DLTGQMTIGW
     NLGNTLDAYG GSSTAAPEKY VTTWGNPAPT QATFDAIKKA GFNTVRIPTT WYPHVTFDTT
     SQTYVVDETW MNYVKQVVDF AYQQDMFVIL NVHHEETWIN VSQFTDETLE TAKKMLSDIW
     TQIATTFQDY DQHLVFEGMN EPRQKANSAV GEWGNGSGDN GYTWSYINTL NAVFVQTVRS
     QGSSANQERL LMLPGYCASS DPVAINQITV PENAGNVALS VHAYAPYFFT MDTSDYANHS
     FPGKSGWGED YETNLTNLFQ SLKSISDSKQ VPIIIGEFSA SDFENTADRE RWATSYLTHA
     KEAGIPCVLW DNNVSANGTG EAHGYLYRLT NTWYPNSISV IRAMMAVYDI TPELPEYEEY
     VAPTFSWDDM QIGEDWVELY KKEAGKSLAA WKNAMVLTDW KTYLKPGAKF VMFADTTSDP
     ELVLQGGWYR LASSGSTGTF VYEFSYESIV EALEAEGANL DDMQNLYVSA TAQAAKIYGL
     YAVPAKSSSE TVLGDLNGDG ELTILDAVLM QRFLLGDLTL TDEQAAVMDC NEDGVWNAFD
     GAYLKRKLLL PMAEGVQ
//