ID   R7H4V0_9FIRM            Unreviewed;       335 AA.
AC   R7H4V0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Kinase PfkB family {ECO:0000313|EMBL:CDE34028.1};
GN   ORFNames=BN645_00411 {ECO:0000313|EMBL:CDE34028.1};
OS   Ruminococcus sp. CAG:403.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1262958 {ECO:0000313|EMBL:CDE34028.1, ECO:0000313|Proteomes:UP000017925};
RN   [1] {ECO:0000313|EMBL:CDE34028.1, ECO:0000313|Proteomes:UP000017925}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:403 {ECO:0000313|Proteomes:UP000017925};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC       {ECO:0000256|ARBA:ARBA00010688}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE34028.1}.
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DR   EMBL; CBIS010000209; CDE34028.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7H4V0; -.
DR   STRING; 1262958.BN645_00411; -.
DR   Proteomes; UP000017925; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd01167; bac_FRK; 1.
DR   Gene3D; 3.40.1190.20; -; 1.
DR   InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR   InterPro; IPR011611; PfkB_dom.
DR   InterPro; IPR029056; Ribokinase-like.
DR   PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43085:SF54; PUTATIVE-RELATED; 1.
DR   Pfam; PF00294; PfkB; 1.
DR   SUPFAM; SSF53613; Ribokinase-like; 1.
DR   PROSITE; PS00583; PFKB_KINASES_1; 1.
DR   PROSITE; PS00584; PFKB_KINASES_2; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CDE34028.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017925};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          3..313
FT                   /note="Carbohydrate kinase PfkB"
FT                   /evidence="ECO:0000259|Pfam:PF00294"
SQ   SEQUENCE   335 AA;  36895 MW;  6DAA197ED7E7CD1E CRC64;
     MKQTITTIGE ALIDFIPEQR DCPLKEVTTF YRVCGGAPTN VAAAIGKLGG KARMITQVGN
     DAFGDYIVDQ LEKCGIDTES ICRTDAANTA LAFVSLKTDG NRDFSFYRKP SADMLMEPEQ
     LQPAWLEDTA VLHFGSVSLV ESPMKQTHVR AIQLAKEQGA IISFDPNIRL PLFPSAEACQ
     AAVREFLPYV DLLKVSDEEL EFVTGETDIQ KAAPLLFEQG CKMILYSKGK QGAMLLTPQV
     VCTEPNPKVK VKDTTGAGDA ICGAFLYCLG KNGITPENLN QQPAGKLQKW LRYAVYYANY
     SVTGSGAITS YPDDETFQRW LRTFDSFIAV RKNEL
//