ID R7H8S9_9FIRM Unreviewed; 638 AA.
AC R7H8S9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=NADH:flavin oxidoreductases Old Yellow Enzyme family {ECO:0000313|EMBL:CDE35711.1};
GN ORFNames=BN634_00229 {ECO:0000313|EMBL:CDE35711.1};
OS Eubacterium sp. CAG:38.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Eubacterium.
OX NCBI_TaxID=1262889 {ECO:0000313|EMBL:CDE35711.1, ECO:0000313|Proteomes:UP000017954};
RN [1] {ECO:0000313|EMBL:CDE35711.1, ECO:0000313|Proteomes:UP000017954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:38 {ECO:0000313|Proteomes:UP000017954};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: In the N-terminal section; belongs to the NADH:flavin
CC oxidoreductase/NADH oxidase family. {ECO:0000256|ARBA:ARBA00011048}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE35711.1}.
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DR EMBL; CBIU010000039; CDE35711.1; -; Genomic_DNA.
DR AlphaFoldDB; R7H8S9; -.
DR STRING; 1262889.BN634_00229; -.
DR Proteomes; UP000017954; Unassembled WGS sequence.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd02803; OYE_like_FMN_family; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR001155; OxRdtase_FMN_N.
DR PANTHER; PTHR42917; 2,4-DIENOYL-COA REDUCTASE; 1.
DR PANTHER; PTHR42917:SF2; 2,4-DIENOYL-COA REDUCTASE [(2E)-ENOYL-COA-PRODUCING]; 1.
DR Pfam; PF00724; Oxidored_FMN; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000017954}.
FT DOMAIN 7..334
FT /note="NADH:flavin oxidoreductase/NADH oxidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00724"
FT DOMAIN 378..604
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT REGION 262..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 638 AA; 69718 MW; CB439D2506709C2F CRC64;
MNQFSHLFEP IRIGKQTVKN RIFMPPLSTN LADKGYVTDA LIEHYSNRAK GGVGLIVTEV
TTVEPTYTYL PGDMSIYDDS YIPGWKKLVD AVHQYDTKIL SQLFHPAYMA FPLPGTPQLI
APSNVGPYYA KAAPRAATVE ELHVIVRQFG EAAHRFQQAG GDGVEIQCAH AHGLLGGFLT
PLYNKRTDEY GGDINGRLRL TLEVIEEVRK MCGEDFIIDV RISGDEYSDG GLTLNDMIYV
SKQLEKAGVD FIHVSGGNTI KRGSSMPAPG TAPAPHAHSS EEIKKHVHIP VATVARINEP
WIAEELIANG KTDICMIGRP NLCDSEFANK AYAGKTEDIR PCIGCGRCLT GIMFGKPISC
TVNPSVETNA IEEAPEKKKV LVIGGGPAGM EAAYVAKKRG HEVVLCEKSN ELGGLLRIAA
VPISKQELCK VIKFMAHRLQ NEGIEVRMNC EVTPEMLETE FKDYEVVCSI GAKPKEIEGF
KKFKQTMTAD DILAGRTFPG RKIVILGGGS VGCETADYLA PLINDLFPAN RDVTILEMTP
SLMTGEGGAA KSQLTQRLMR KGVKIELNSQ VTKVDENTIT YVKEGVEHHI DDADTLVFAV
GYTPLKMENE RVNYIGDCDK VGNLKDAIGA AYQLAKTL
//
