ID R7HZI2_9CLOT Unreviewed; 498 AA.
AC R7HZI2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Cell wall-associated hydrolases (Invasion-associated proteins) {ECO:0000313|EMBL:CDE44666.1};
GN ORFNames=BN648_02147 {ECO:0000313|EMBL:CDE44666.1};
OS Clostridium sp. CAG:411.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262802 {ECO:0000313|EMBL:CDE44666.1, ECO:0000313|Proteomes:UP000018022};
RN [1] {ECO:0000313|EMBL:CDE44666.1, ECO:0000313|Proteomes:UP000018022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:411 {ECO:0000313|Proteomes:UP000018022};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE44666.1}.
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DR EMBL; CBIY010000087; CDE44666.1; -; Genomic_DNA.
DR AlphaFoldDB; R7HZI2; -.
DR STRING; 1262802.BN648_02147; -.
DR Proteomes; UP000018022; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR003646; SH3-like_bac-type.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR34408; FAMILY PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR34408:SF1; GLYCOSYL HYDROLASE FAMILY 19 DOMAIN-CONTAINING PROTEIN HI_1415; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF08239; SH3_3; 2.
DR SMART; SM00287; SH3b; 2.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
DR PROSITE; PS51781; SH3B; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:CDE44666.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018022}.
FT DOMAIN 52..114
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 184..247
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 377..498
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
SQ SEQUENCE 498 AA; 55414 MW; EBF3946F545E1BAC CRC64;
MRRMRKGVAA VTCAICVAST VFVGSFIAKS VISKADNMEI KVGDLTVSVP EEMLAAKVNS
FLNIRYQPSS SSTIIGELKP GDTVTYLETL GEWTKVDVNG QIGYVYTKYA LTGNSLKKYI
KNNLDKFSVE AVQTEESFSK VYKTKKGARA DAATYEMNGK VKKTATIYAT KSSAQTIKNE
YETVKKAVVN VQALRLRENA STKSPIKAVL SKGTYLTIVS DAKKDWMKVK YDGKIGFVSK
DYIRVANVKQ NKSNIVKTVK KDTKLNVEQV EKNWVQVSCD GVKNYMKREY CNVSAQTDDK
KVTGLLENNV SCKIKNVQDD IALVTLKDGS QGYIKCANLK AQISIDGVKI NEAAVNAEQK
KIEEKQNIQI KNDGKVSKKR TDIVNYALKF VGNPYKWGGN SLTEGTDCSG FVNLIYKKYG
YNLARCSWLQ AQNGKEISFS ELQPGDLIFY YDKDLGRIGH VAIYMGNNKI VHAKSTKAGI
TTNEWNYRTP YKAVNVID
//
