ID   R7I0K4_9CLOT            Unreviewed;       614 AA.
AC   R7I0K4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=GP-PDE domain-containing protein {ECO:0000259|PROSITE:PS51704};
GN   ORFNames=BN648_01908 {ECO:0000313|EMBL:CDE44052.1};
OS   Clostridium sp. CAG:411.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1262802 {ECO:0000313|EMBL:CDE44052.1, ECO:0000313|Proteomes:UP000018022};
RN   [1] {ECO:0000313|EMBL:CDE44052.1, ECO:0000313|Proteomes:UP000018022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:411 {ECO:0000313|Proteomes:UP000018022};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE44052.1}.
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DR   EMBL; CBIY010000075; CDE44052.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7I0K4; -.
DR   STRING; 1262802.BN648_01908; -.
DR   Proteomes; UP000018022; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd08579; GDPD_memb_like; 1.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   InterPro; IPR018476; GlyceroP-diester-Pdiesterase_M.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   PANTHER; PTHR46211; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR   PANTHER; PTHR46211:SF8; PHOSPHODIESTERASE-RELATED; 1.
DR   Pfam; PF03009; GDPD; 1.
DR   Pfam; PF10110; GPDPase_memb; 1.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018022};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        133..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          362..593
FT                   /note="GP-PDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51704"
SQ   SEQUENCE   614 AA;  70727 MW;  9E5A578BD822FFBA CRC64;
     MKKKRECGRR IKHTWAMQVE GLKWLYVFQV IYAITSILLF RPLCNFVIRK LLRLYGYSYI
     TSENMLLFFG KLPVIGALLL LLLLFALFSF LALMYIYRYI SDVCHRKNVN CFSNVLSTYK
     DVKRLLLERQ YSAVFLVIGT GLLYAMPIIF FAMKNIPSVH YVVKSFLKIK ELKRMLYIGM
     VLFLGVMLRH TYTLSSFFEG ESSFKKAKET SKKIFLRRPI RTVVGILFWN LVSVGFCGIC
     YTIIIGITIL LILLFVSNNL HVAVFCTVQE KLYFMGFSLS LLFSITLQIT GNLQFFDWVK
     EKSEKYEESE KISTKEKYAG TKLLNKKLFI SGIILVLILD SVAIYDTIQN GKSSNWGKNG
     NAEITSHRGA SFYAPENTIP AMENAISQAT DYIEIDVQQT KDGEVVLMHD SLMTRTAGVS
     KHVYEMTYEE IKQLDAGKWY SPEYAGTTIP TLREVLRFCK GKCKLNIEVK ASDKTPGLIE
     KVVDLIEEYD FTRQCVVTSV YKKALCEVKK YNKEIVTGYI LSSAYGRYYL DKDIDFLSMR
     VTMVTERIVL LAHKYGKEVY VWTVNSKQDA LYMSQLGVDN IITDRPAYIR NALYEENANR
     TILNLLRIGF QQGD
//