ID R7J7U5_9FUSO Unreviewed; 631 AA.
AC R7J7U5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Diguanylate cyclase and metal dependent phosphohydrolase {ECO:0000313|EMBL:CDE59935.1};
GN ORFNames=BN657_01875 {ECO:0000313|EMBL:CDE59935.1};
OS Fusobacterium sp. CAG:439.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=1262899 {ECO:0000313|EMBL:CDE59935.1, ECO:0000313|Proteomes:UP000018397};
RN [1] {ECO:0000313|EMBL:CDE59935.1, ECO:0000313|Proteomes:UP000018397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:439 {ECO:0000313|Proteomes:UP000018397};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE59935.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBJH010000048; CDE59935.1; -; Genomic_DNA.
DR AlphaFoldDB; R7J7U5; -.
DR STRING; 1262899.BN657_01875; -.
DR Proteomes; UP000018397; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CDE59935.1}.
FT DOMAIN 270..400
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 441..631
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 631 AA; 71453 MW; A5C53CEE5351B2B5 CRC64;
MSFFDNLKDI YRKVSEVESA VYNGKQDYLE IYERNLQLEK EIEERTRELN IANKRMLTLQ
HIWDMMNASR PLQSVLETIV NSIQGELGYL HCNIIKKCED EKGIYLTVLA QSNDVSIKRV
DKLIKGPIQA RKLVYDETSV YAKAALEKKI MLTPDIGGTL KSVAPDVPDE IIEEVVEGSP
SKSIITVPLF TRNSHYGWFN VFSSRKDLTS GETDFLTIFA QQIEMAITIA GLFEEVKAQA
VTDGLTGLYN RRYFEEYLKK EVTRAMRQKQ AFSVIGLDLD HLKQINDKYG HAYGDLAIKT
VAEVLKKNAR SIDTAARMGG EEFNVILPGV DSSGAMIAAE RIRKALEEEK LDTIGHITAS
IGVATFLEHS DNIEDILELT DQAMYSSKRN GRNLVTLAKP VSETSWQEIA VNTFMDILSK
HNIPLAKDVS EELKNKLQNP KDDVPKEALY TVADMLTQTY NPLHHNGVMK SKVLLAVSLA
KRFDLPKDDI DRLRIAMLLY DIGNLMLPAS LLQKTTPLTE EERNHIKEHP IIAAREILKP
ISYIQDIIPI IEHHHENWDG TGYPAKIARE KIPMTSQIIL IVDAYFALTE PRTYRAELTP
KQAVEVIKQD AGKKWNSALV QEFISLIDHD V
//
