ID R7K8E1_9FIRM Unreviewed; 590 AA.
AC R7K8E1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:CDE71282.1};
GN ORFNames=BN603_00764 {ECO:0000313|EMBL:CDE71282.1};
OS Subdoligranulum sp. CAG:314.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Subdoligranulum.
OX NCBI_TaxID=1262970 {ECO:0000313|EMBL:CDE71282.1, ECO:0000313|Proteomes:UP000017993};
RN [1] {ECO:0000313|EMBL:CDE71282.1, ECO:0000313|Proteomes:UP000017993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:314 {ECO:0000313|Proteomes:UP000017993};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE71282.1}.
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DR EMBL; CBJL010000031; CDE71282.1; -; Genomic_DNA.
DR AlphaFoldDB; R7K8E1; -.
DR STRING; 1262970.BN603_00764; -.
DR Proteomes; UP000017993; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR023862; CHP03960_rSAM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR045784; Radical_SAM_N2.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR NCBIfam; TIGR03960; rSAM_fuse_unch; 1.
DR PANTHER; PTHR42731:SF6; RADICAL SAM DOMAIN PROTEIN; 1.
DR PANTHER; PTHR42731; SLL1084 PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF19864; Radical_SAM_N2; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017993}.
FT DOMAIN 240..479
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 590 AA; 66506 MW; 455857B674F9BC88 CRC64;
MKLSESISKP ARYTGGEYGA PDTSKPFDTS VCLCFPDVYE VGMSNLGTRI LYFLMNGLDG
VVCERCYAPW TDYADFLRDE GSPLVSLENK KPFKDFDFVG FSLQYELSYS NMLLMLDLAG
FPLLAKDRGD EFPIVIAGGP CTVNPEPVAA FVDIFMLGEG ETPWPQLLEL YKLNRGMKKR
DFLRLAADTL DCLYLPERVN VRTENGRTVE VRYEKKVKKH KEKNLDESFF PKTALVPNLE
IVHDRAVAEL FRGCANGCRF CQAGFIYRPV RERSPDTVVA ICRSLLLSTG YDELSLNSLS
TGDYSGLKEI VTRLKPFVKE RGVKLSLPSL RMDSFDGETA DTERKSSLTF APEAGTQRLR
DVINKNITEE NIFNTLAQAF ERGYSSVKFY FMLGLPTETD EDVDGIVNLA AAVKKLYRER
RTSGKELRLS ISAATFIPKP FTPFQWEGFA QREDIERKQS YLKFRLKKLG VGFSYHDYDT
SFMEALLARG GREMSAVLLE AYSGGARFDS WDEHFDFKIY DAALKKCGTD VGAVVGKKSF
DEVLPWDFVD VGVEKSYLKR EAERAYAAKT TPSCLKQCNG CGLQKEGLCK
//
