ID R7L2A3_9BACT Unreviewed; 1231 AA.
AC R7L2A3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN ORFNames=BN601_00600 {ECO:0000313|EMBL:CDE82784.1};
OS Coraliomargarita sp. CAG:312.
OC Bacteria; Verrucomicrobiota; Opitutae; Puniceicoccales;
OC Coraliomargaritaceae; Coraliomargarita.
OX NCBI_TaxID=1262865 {ECO:0000313|EMBL:CDE82784.1, ECO:0000313|Proteomes:UP000017918};
RN [1] {ECO:0000313|EMBL:CDE82784.1, ECO:0000313|Proteomes:UP000017918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:312 {ECO:0000313|Proteomes:UP000017918};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE82784.1}.
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DR EMBL; CBJS010000012; CDE82784.1; -; Genomic_DNA.
DR AlphaFoldDB; R7L2A3; -.
DR STRING; 1262865.BN601_00600; -.
DR Proteomes; UP000017918; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000017918}.
FT DOMAIN 2..1215
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT DOMAIN 527..629
FT /note="SMC hinge"
FT /evidence="ECO:0000259|Pfam:PF06470"
FT COILED 165..206
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 246..490
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 682..842
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 875..919
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1231 AA; 138614 MW; 9F89ABDCF009CCAC CRC64;
MYLKQVTING FKSFADKTEL PLTPGITCIV GPNGCGKSNI VDAIRWVLGE QSAKALRGGK
MQDVIFQGTE TRKPLQFCDV SLLFTDCEKQ LKFNEVEITR KVYRDGGSDY FINGKSARLK
DIQNLFMDTG VGRVSYSFMV QGQIDQILSS NPGERRTIFE EAAGITKYKT QRREALNKLA
LVEQNLARAT DRIEEISRQI GTLKRQASKA LRYKRLSYRL RHLDLALNSH NYAKQNALLK
EDETVQKRLS SEILELSEKL AACEEDLSRM RASRAELLAQ LESLRQNASE VRSAKEQAER
NSEFAEVRKR DLGERLEQIS KELESLKEQL SALEGKAQGD IEVKQMQLNL VSADDEVFRQ
QSAELAEVEE SLRDAENRLS RAKQDSLMNE SAVTRLRSNC TTLEVDLKSY QVRHAALSDQ
IFQLKEENSS LERRCEELSA AMENANERLG NAEADITEAV AKADELRAQY RNQQAEIQQM
DRQLASKSAK LSLLNDLQSR MEGFSEGVKA IMKGRLGECL DPLNLKIVSQ NVEVADGWTS
AFETMLGSAV DAVAIEDSSK LPQALALLRE RNLGNACFQI KDANLNAISD ADALPQGIWR
GCDIVKPQDP DLSEYVRNMV AGCYFCEDIM QFANFALNNK NFKFMAAVAK DGSMLDARGI
IYASSGEKRD TQSSFILRNS EIKRIKEEIE VDNDALTTLN ERAMQIQSQL ESAEAEIENR
KNLSSEIKRE IASINAQSSS AKAAFSEKNS EIEKKTAAMA EMENSRFEAQ DRLNSAMKAL
EDAEKSISES RNLISETEAQ IAELRETKDQ KYAVLSETRL ELAAKKSRLE SLERGLGAIR
EQQAETRALI ERRTIESQSI ARQIENFDAE TLSERERAKN LAENLEAALG EIEAQRVKVA
ESETSIAEYE NSLSAEREAH MRKTSEKNEC QIRIAKIRSK LDFISERILS EYDVEIANVD
WKSELWKSDE EFEIKVKLDE LEDGEINAKP KRERGDPTQD DLDAMESTDF SPIEDEVREL
RERINAMGAV NLVAIEEYAE LKERYDFLKT QTDDLWASKN ALVADIDEIN ATSQKLFSET
FEQIRKNFAF TFQKIFGGGT ADLRLVESED VLDSGIEIVA RPAGTVLKSL SLLSGGQRTM
TAVSLLFAIY MVKPSPFCVL DELDAPLDDA NIGRYTDMLK EFTRYSQFLV ISHNKRTMSA
AQTLYGVTMQ ERGVTRLISM RFNGESTSSG E
//
