ID   R7LJG1_9BACT            Unreviewed;       720 AA.
AC   R7LJG1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Arylsulphatase A {ECO:0000313|EMBL:CDE87843.1};
GN   ORFNames=BN805_00593 {ECO:0000313|EMBL:CDE87843.1};
OS   Prevotella sp. CAG:891.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=1262937 {ECO:0000313|EMBL:CDE87843.1, ECO:0000313|Proteomes:UP000018147};
RN   [1] {ECO:0000313|EMBL:CDE87843.1, ECO:0000313|Proteomes:UP000018147}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:891 {ECO:0000313|Proteomes:UP000018147};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PTM: The conversion to 3-oxoalanine (also known as C-formylglycine,
CC       FGly), of a serine or cysteine residue in prokaryotes and of a cysteine
CC       residue in eukaryotes, is critical for catalytic activity.
CC       {ECO:0000256|PIRSR:PIRSR600917-52}.
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDE87843.1}.
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DR   EMBL; CBJT010000269; CDE87843.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7LJG1; -.
DR   Proteomes; UP000018147; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd16143; ARS_like; 1.
DR   Gene3D; 3.30.1120.10; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR43751:SF5; N-ACETYLGALACTOSAMINE-6-O-SULFATASE; 1.
DR   PANTHER; PTHR43751; SULFATASE; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
DR   PROSITE; PS00149; SULFATASE_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018147}.
FT   DOMAIN          28..401
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
FT   MOD_RES         76
FT                   /note="3-oxoalanine (Ser)"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600917-52"
SQ   SEQUENCE   720 AA;  78867 MW;  C81AF270D212F155 CRC64;
     MNHKTFVLAG LGSFSLLPAL GQTAQSQPNV IFLVADDLGY GDLSCYGATR VETPNVDGLA
     QHGVRFTDAH AVASTSTPSR YSMLTGEYCF RRPGTDIATG DAGMIIRPEQ YTLADMFKSC
     GYTTGAVGKW HLGLGSKTGK QNWNEKLDMG LDDIGFDYYC VMAATADRVP CVYIENGVVK
     DYDSSAPISV SYSKNFAGEP TGKDNPELLT KLKSSHGHNQ AIVNGIGRIG YMKGGGKALW
     RDEDIADSIA ASAIRFIERN ADNPFFLYLC TNDVHVPRYP HERFRGKSVM GLRGEAIMQF
     DYTVGQVMET LRRLNLDENT LIVITSDNGP VLDDGYQDQA RELAGDHKPG GPWRGGKYSA
     FEAGTAVPFI VNWPAAIKQG KVSDALVSHI DLVASMAQLV GAQLPLGAAP DSRDQLETWL
     GRSDEPAPFV AEMAQDHTVS VRTSQWKYIE PSNGAAKQGQ TGIETGYSKK PQLYDISISR
     YETENLIEAQ PEVAKQFSQH LDELRQPKTS ADTCFWYRLL TPQRESRCAT STGVGNGLIG
     KTEAMGADSQ WKFVKRPEGD GYDIVNREDK SYLTPCAVQR PALQLHTSAE RPAEGWVLKT
     NGIMNCLFSV TCGTSQMNQS EKSRNYQILN WGNGTNTTDV GCLYAAVLTD ATVEGIVEGI
     ETVKTDPSKL EVKNGRFVWN GNDKDVELYE ITGKRCSQGK MPTEGIYIVR SGKKAWKIAL
//