ID R7LUL1_9CLOT Unreviewed; 375 AA.
AC R7LUL1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Alanine racemase {ECO:0000313|EMBL:CDE91067.1};
GN ORFNames=BN638_00749 {ECO:0000313|EMBL:CDE91067.1};
OS Clostridium sp. CAG:389.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1262801 {ECO:0000313|EMBL:CDE91067.1, ECO:0000313|Proteomes:UP000017978};
RN [1] {ECO:0000313|EMBL:CDE91067.1, ECO:0000313|Proteomes:UP000017978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:389 {ECO:0000313|Proteomes:UP000017978};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600821-50};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE91067.1}.
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DR EMBL; CBJV010000109; CDE91067.1; -; Genomic_DNA.
DR AlphaFoldDB; R7LUL1; -.
DR STRING; 1262801.BN638_00749; -.
DR Proteomes; UP000017978; Unassembled WGS sequence.
DR GO; GO:0008784; F:alanine racemase activity; IEA:InterPro.
DR GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR CDD; cd00430; PLPDE_III_AR; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR000821; Ala_racemase.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR011079; Ala_racemase_C.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR029066; PLP-binding_barrel.
DR NCBIfam; TIGR00492; alr; 1.
DR PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR Pfam; PF00842; Ala_racemase_C; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR PRINTS; PR00992; ALARACEMASE.
DR SMART; SM01005; Ala_racemase_C; 1.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR600821-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000017978}.
FT DOMAIN 247..375
FT /note="Alanine racemase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01005"
FT MOD_RES 41
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600821-50"
SQ SEQUENCE 375 AA; 42753 MW; D631C00F64635468 CRC64;
MKSVVINKED LRYNIEKIKE YAETNLPDDK GRKVKIIAVV KANGYGFGIV EYSQFLIDNG
IDFLAVSTVE EALKIRQAGI TEKEAKILML SSTAVKEDVK TLIENNIILT IGSKEAVDVV
DEVGQELEKK IKVHLKIDTG FGRYGFLYDN RDEMIKCLKK VKNIKIEGTY THFSNSYYDD
KYTEKQFDRY MKCIEVLKMN EIETGMLHVC NTSAFIKFPN MHLNAVRVGS GFTGKIAFKN
SMGLRKIGYL KSNVAEIKVL PKDFNIGYSN AYKTQKETKV AIIPCGYMDG VNIQTGRDMF
RMVDKIRYIV RDIKDALKKQ QIFVTINGKK CPVLGRVGTY HVTVDITGKD VNINDEVIFN
ANLKHIDSSI RREWK
//
