ID R7LZH2_9FIRM Unreviewed; 697 AA.
AC R7LZH2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Peptidoglycan glycosyltransferase {ECO:0000313|EMBL:CDE93840.1};
GN ORFNames=BN701_01363 {ECO:0000313|EMBL:CDE93840.1};
OS Acidaminococcus sp. CAG:542.
OC Bacteria; Bacillota; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC Acidaminococcus.
OX NCBI_TaxID=1262687 {ECO:0000313|EMBL:CDE93840.1, ECO:0000313|Proteomes:UP000018195};
RN [1] {ECO:0000313|EMBL:CDE93840.1, ECO:0000313|Proteomes:UP000018195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:542 {ECO:0000313|Proteomes:UP000018195};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDE93840.1}.
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DR EMBL; CBJX010000099; CDE93840.1; -; Genomic_DNA.
DR AlphaFoldDB; R7LZH2; -.
DR STRING; 1262687.BN701_01363; -.
DR Proteomes; UP000018195; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.770; -; 1.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR PROSITE; PS51178; PASTA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CDE93840.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 639..697
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 697 AA; 75076 MW; 0C772D2094B2E9AF CRC64;
MKRPSFFSPK KKNTPQAPRE PVLKLDPTHQ AVLHEGKLRA VILGKVLGVA VLAIILRLFW
LQVIQGSTLA QEANDQITGE HTEIAPRGSI VDRNGEELAV SVVSKSLYVD PQELVDNPER
WPAGKMPSRD PKRVAADALA PVLDLKADQL YKEFCEPDRR FIWVKRTLDP HEADQVEAIL
KDQKLSGFHF KEESKRFYTK NDLAAQVLGF VGTDDQGLEG MEASMDEELK GRKQKKRSFF
DAKGKLVGRS ALNQVQVRRM NTVQLTIDAR MQFILEKSLD EAIKKTHAAS AAAILMDPNT
GEILGMASRP TFDPNHFGNA PKGAYMNRGV GIVYEPGSVF KPIMGSAGLM EGVITPNTPF
NDQGSIDVGG RRIRNWDGKG MGHVTFTDVI KFSLNTGMAD LGLKLGGERE TQYAKAFGFG
SVTGSDVPGE EAGILYNPKD MVPSDVATMA IGQGIAVTPL QMLRAICAIA NGGNLVKPYI
VKKVTSPDGQ VLKEGKTEVV RTVITPEVAE EMRTMMEKVV SEGGGKTAQI KGYKIAGKTG
TAEKLSPKGG YIPGVYIASF VGFVPSDAPR YAMIIMLDSP KGAFYGSQVS APIFRDTLQQ
ILVAEGVQPS NWDGIPTVES LLAKTAKEAA PLVTLEADGN GAVKLSNLAG HSIREVAGAL
GGAGLSLIPV GSGTSWKQNP APGTVLHSGD TVTVYFR
//
