ID R7MHQ6_9FIRM Unreviewed; 545 AA.
AC R7MHQ6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Beta-xylanase {ECO:0000256|RuleBase:RU361174};
DE EC=3.2.1.8 {ECO:0000256|RuleBase:RU361174};
GN ORFNames=BN739_00627 {ECO:0000313|EMBL:CDF00634.1};
OS Ruminococcus sp. CAG:624.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=1262965 {ECO:0000313|EMBL:CDF00634.1, ECO:0000313|Proteomes:UP000017977};
RN [1] {ECO:0000313|EMBL:CDF00634.1, ECO:0000313|Proteomes:UP000017977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:624 {ECO:0000313|Proteomes:UP000017977};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.;
CC EC=3.2.1.8; Evidence={ECO:0000256|RuleBase:RU361174};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 10 (cellulase F) family.
CC {ECO:0000256|ARBA:ARBA00007495, ECO:0000256|RuleBase:RU361174}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF00634.1}.
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DR EMBL; CBKC010000045; CDF00634.1; -; Genomic_DNA.
DR AlphaFoldDB; R7MHQ6; -.
DR STRING; 1262965.BN739_00627; -.
DR Proteomes; UP000017977; Unassembled WGS sequence.
DR GO; GO:0031176; F:endo-1,4-beta-xylanase activity; IEA:UniProtKB-EC.
DR GO; GO:0045493; P:xylan catabolic process; IEA:UniProtKB-KW.
DR CDD; cd14256; Dockerin_I; 1.
DR Gene3D; 1.10.1330.10; Dockerin domain; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR003305; CenC_carb-bd.
DR InterPro; IPR002105; Dockerin_1_rpt.
DR InterPro; IPR016134; Dockerin_dom.
DR InterPro; IPR036439; Dockerin_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR044846; GH10.
DR InterPro; IPR031158; GH10_AS.
DR InterPro; IPR001000; GH10_dom.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31490:SF88; BETA-XYLANASE; 1.
DR PANTHER; PTHR31490; GLYCOSYL HYDROLASE; 1.
DR Pfam; PF02018; CBM_4_9; 1.
DR Pfam; PF00404; Dockerin_1; 1.
DR Pfam; PF00331; Glyco_hydro_10; 1.
DR PRINTS; PR00134; GLHYDRLASE10.
DR SMART; SM00633; Glyco_10; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF63446; Type I dockerin domain; 1.
DR PROSITE; PS51766; DOCKERIN; 1.
DR PROSITE; PS00591; GH10_1; 1.
DR PROSITE; PS51760; GH10_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|RuleBase:RU361174};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361174};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361174};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|RuleBase:RU361174};
KW Reference proteome {ECO:0000313|Proteomes:UP000017977};
KW Xylan degradation {ECO:0000313|EMBL:CDF00634.1}.
FT DOMAIN 99..429
FT /note="GH10"
FT /evidence="ECO:0000259|PROSITE:PS51760"
FT DOMAIN 472..543
FT /note="Dockerin"
FT /evidence="ECO:0000259|PROSITE:PS51766"
FT REGION 73..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 361
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10061"
SQ SEQUENCE 545 AA; 59295 MW; 18AFA815A95DD4DC CRC64;
MRLTLQYQDA SGETQYDTVA SANAKSTEWT KLENTAYTIP SGASDLLLYV ENADSTADFY
MDEAIGAVKG TASTVTTGQG TSGSQTGTTD PGTDPGSSDV STGYLKDAFA GLFKFGTSVS
PNELNSGATF IKNHFNSITP ENELKPDAIL NQSASQQYGN NVNPQVTFNS GTQATLKFCE
QNGISMRGHT FVWYSQTPDW FFRENFSSSG AYVSKEIMNQ RMENFIKNTF ELIAKDYPNL
DLYAYDVVNE AFLNDGGGLR DANNSNWTKI YGDSDEFIIN AFTYARKYAP AGCKLYINDY
NEYIPAKTND LYNIAMKLKE KGLIDGIGMQ SHLDVGYPSA SLYKTALEKF ISTGLDVQIT
ELDITTTNES SQAALYKEIL QLAVDHADSI SSVTVWGTHD SISWRSSQNP LLFGANYTPK
QAYTAVMEVA KNATPPQTTT TTKITTTTTK ATTTTTTTKA TTTTKATTTQ PVNYLPGDAN
CDGKVDISDA VVIKCYLISS SKYPLSAQGA YNADVQGNRN GVNAQDAVAI QKYILRIITS
FDAVS
//
