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Database: UniProt
Entry: R7PMS6_9FIRM
LinkDB: R7PMS6_9FIRM
Original site: R7PMS6_9FIRM 
ID   R7PMS6_9FIRM            Unreviewed;       251 AA.
AC   R7PMS6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   12-APR-2017, entry version 21.
DE   SubName: Full=Chromosomal replication initiator protein DnaA {ECO:0000313|EMBL:CDF26954.1};
GN   ORFNames=BN722_00774 {ECO:0000313|EMBL:CDF26954.1};
OS   Dialister sp. CAG:588.
OC   Bacteria; Firmicutes; Negativicutes; Veillonellales; Veillonellaceae;
OC   Dialister; environmental samples.
OX   NCBI_TaxID=1262871 {ECO:0000313|EMBL:CDF26954.1, ECO:0000313|Proteomes:UP000018383};
RN   [1] {ECO:0000313|EMBL:CDF26954.1, ECO:0000313|Proteomes:UP000018383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:588 {ECO:0000313|Proteomes:UP000018383};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J.,
RA   Sunagawa S., Plichta D., Gautier L., Le Chatelier E., Peletier E.,
RA   Bonde I., Nielsen T., Manichanh C., Arumugam M., Batto J.,
RA   Santos M.B.Q.D., Blom N., Borruel N., Burgdorf K.S., Boumezbeur F.,
RA   Casellas F., Dore J., Guarner F., Hansen T., Hildebrand F., Kaas R.S.,
RA   Kennedy S., Kristiansen K., Kultima J.R., Leonard P., Levenez F.,
RA   Lund O., Moumen B., Le Paslier D., Pons N., Pedersen O., Prifti E.,
RA   Qin J., Raes J., Tap J., Tims S., Ussery D.W., Yamada T.,
RA   MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P., Wang J.,
RA   Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units
RT   of genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CDF26954.1}.
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DR   EMBL; CBKO010000028; CDF26954.1; -; Genomic_DNA.
DR   Proteomes; UP000018383; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018383};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018383}.
FT   DOMAIN      158    227       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   251 AA;  29589 MW;  C2033785892CD014 CRC64;
     MEQFRRRYRH VDYFLMDDVQ LFSGKNSSQV EVFNTFNVLF DNKKHIILTS DRTPQDIEKL
     EDRIKTRFSS GLIAPIEPPD YEMCSVILLK KAENDNILLP EEVVNYIAGH IHTNVRELNG
     AYNKLVSNAI LTKQEITLEN TKELLRDIIP FDKKKELNMD FITDVVCQYY GISKSSVLSK
     SRPKKIVTPR QMAMYFCRQE LNESYPNIRD FFKRKDHTTV MYACERVDED LKTKPAIKED
     YDKIKKILES R
//
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