ID R7QYT0_9FIRM Unreviewed; 342 AA.
AC R7QYT0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Aldo/keto reductase {ECO:0000313|EMBL:CDF42601.1};
GN ORFNames=BN520_01726 {ECO:0000313|EMBL:CDF42601.1};
OS Roseburia sp. CAG:182.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1262942 {ECO:0000313|EMBL:CDF42601.1, ECO:0000313|Proteomes:UP000018104};
RN [1] {ECO:0000313|EMBL:CDF42601.1, ECO:0000313|Proteomes:UP000018104}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MGS:182 {ECO:0000313|Proteomes:UP000018104};
RA Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA Wang J., Brunak S., Ehrlich S.D.;
RT "Dependencies among metagenomic species, viruses, plasmids and units of
RT genetic variation.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDF42601.1}.
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DR EMBL; CBKT010000197; CDF42601.1; -; Genomic_DNA.
DR AlphaFoldDB; R7QYT0; -.
DR STRING; 1262942.BN520_01726; -.
DR Proteomes; UP000018104; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd19100; AKR_unchar; 1.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43312:SF1; ALDO_KET_RED DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43312; D-THREO-ALDOSE 1-DEHYDROGENASE; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR Pfam; PF13534; Fer4_17; 1.
DR PRINTS; PR00069; ALDKETRDTASE.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018104}.
FT DOMAIN 294..326
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 342 AA; 38295 MW; A1B2F6A70315D082 CRC64;
MEQVTLGSTG ITVNKNGFGA LPIQRITDED AVHLVRKAYD AGITFFDTAR FYTDSEEKLG
IALEGIRDKV FVATKTAASN AKEFFEQLET SLHNLRTDYV DIYQFHNPAV CPKPGDGSGL
YEAMLEAKEK GMIRHIGITN HRLAVADEAI ESGLYETLQF PFCYLANDQD IALVEKCKEK
NMGFIAMKAL SGGLITNSRA AYAFEAQYDN VLPIWGVQRE KELDEFISYI EHPPVMTDEI
KALIEADRKE LSGEFCRGCG YCMPCPAGIE INNCARMSLL LRRSPSELQL TKEVQEKMKK
IENCLHCGHC KSKCPYGLDT PALLEKNYED YKRVLAGEVS VK
//
