ID   R7R7R9_9FIRM            Unreviewed;       680 AA.
AC   R7R7R9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13649};
GN   ORFNames=BN450_02213 {ECO:0000313|EMBL:CDF45750.1};
OS   Roseburia sp. CAG:100.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262940 {ECO:0000313|EMBL:CDF45750.1, ECO:0000313|Proteomes:UP000018092};
RN   [1] {ECO:0000313|EMBL:CDF45750.1, ECO:0000313|Proteomes:UP000018092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:100 {ECO:0000313|Proteomes:UP000018092};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF45750.1}.
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DR   EMBL; CBKV010000204; CDF45750.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7R7R9; -.
DR   Proteomes; UP000018092; Unassembled WGS sequence.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018092}.
FT   DOMAIN          77..150
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
SQ   SEQUENCE   680 AA;  78390 MW;  6B3EFDB580A4E7E0 CRC64;
     MTEKIGNVVL DMTYYPGEDH YSDGDIEDEL LQVAMEHEEE EFPKIIAERK SWPFFYHLSP
     FRTNIIDWLP FKKTDRVLEI GSGCGAITGA LAKRVGSVTC IDLSKKRSLV NAYRNKKQDN
     ITIMVGNFKD IEPHLSCDYD YVLLIGVFEY GRAYIGGETP YEDFMSICNR HRKDSGRLVI
     AIENKFGLKY WAGCREDHLG TYFTGIEGYH TGGVARTFTR RGLEEILHKT GISEYAFYYP
     YPDYKFPTTV YSDEYMPKKG ELSNNLRNFD RDRVLLFDEK QVFDQVIEEG EFPLFSNSYF
     LLIGKKPQTV YAKFSNDRAK AWAIRTLIHK SAAGTFLVEK QPNDKDANAH IVHTYQAYEA
     LSKRYEGTKI RMNECKRTPQ SIVFPFCPGK TLEELLDERL DEQDAEGFRK LIEEYMYWLS
     YNEEANVSNI DFIFPNILVD GDTWHVIDYE WTFDRKVPAK DIAFRAFYNY LLGGEGRKAC
     EELLMQDVLH LTEEEKQQAI QDEQDFQHYV TGDRASVSAM RELIGFKAYE LSGMEAYCVY
     AAAKYVSQVF YDYGEGFSQE NSILIHDCFT EEKDVHFTVD VPKGVKQIRI DPCSYRCAVT
     VKDIAAGEQH FAKDNMTVNG VWANENCVIF DTEDPNLVFA CEGADRLDVT LEVVELPESL
     TATLIEVVTP KENGLKRFFH
//