ID   R7RAQ9_9FIRM            Unreviewed;       240 AA.
AC   R7RAQ9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN450_00702 {ECO:0000313|EMBL:CDF46865.1};
OS   Roseburia sp. CAG:100.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=1262940 {ECO:0000313|EMBL:CDF46865.1, ECO:0000313|Proteomes:UP000018092};
RN   [1] {ECO:0000313|EMBL:CDF46865.1, ECO:0000313|Proteomes:UP000018092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGS:100 {ECO:0000313|Proteomes:UP000018092};
RA   Nielsen H.B., Almeida M., Juncker A.S., Rasmussen S., Li J., Sunagawa S.,
RA   Plichta D., Gautier L., Le Chatelier E., Peletier E., Bonde I., Nielsen T.,
RA   Manichanh C., Arumugam M., Batto J., Santos M.B.Q.D., Blom N., Borruel N.,
RA   Burgdorf K.S., Boumezbeur F., Casellas F., Dore J., Guarner F., Hansen T.,
RA   Hildebrand F., Kaas R.S., Kennedy S., Kristiansen K., Kultima J.R.,
RA   Leonard P., Levenez F., Lund O., Moumen B., Le Paslier D., Pons N.,
RA   Pedersen O., Prifti E., Qin J., Raes J., Tap J., Tims S., Ussery D.W.,
RA   Yamada T., MetaHit consortium, Renault P., Sicheritz-Ponten T., Bork P.,
RA   Wang J., Brunak S., Ehrlich S.D.;
RT   "Dependencies among metagenomic species, viruses, plasmids and units of
RT   genetic variation.";
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDF46865.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CBKV010000342; CDF46865.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7RAQ9; -.
DR   Proteomes; UP000018092; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR42879; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE; 1.
DR   PANTHER; PTHR42879:SF2; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018092};
KW   Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}.
SQ   SEQUENCE   240 AA;  26430 MW;  BA17B4DC12F39F2E CRC64;
     MKRKKALVTG ASRGIGAAIA TALAQEGYDL YLTCHHNMEL LEELACHLEN TCQVSCKCYA
     FPVYEEKAMQ DMFREIPYLD VLVNNAGISY IGLLTDMTYE EWQQVLRTNL DSCFLTSRNA
     LPGMIHRKKG KIINISSVWG NVGASMEVAY SASKGGVNSF TKALAKELGP SNIQVNAIAC
     GVIDTDMNKC FSEEERQELI AEIPADRMGK TQEVAQLVVQ LCTGNEYLTG QIITLDGGWI
//