ID R7SRV4_DICSQ Unreviewed; 789 AA.
AC R7SRV4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=Bromodomain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DICSQDRAFT_90751 {ECO:0000313|EMBL:EJF58495.1};
OS Dichomitus squalens (strain LYAD-421) (Western red white-rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Dichomitus.
OX NCBI_TaxID=732165 {ECO:0000313|EMBL:EJF58495.1, ECO:0000313|Proteomes:UP000053319};
RN [1] {ECO:0000313|EMBL:EJF58495.1, ECO:0000313|Proteomes:UP000053319}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LYAD-421 SS1 {ECO:0000313|EMBL:EJF58495.1,
RC ECO:0000313|Proteomes:UP000053319};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH719435; EJF58495.1; -; Genomic_DNA.
DR RefSeq; XP_007368856.1; XM_007368794.1.
DR AlphaFoldDB; R7SRV4; -.
DR GeneID; 18844892; -.
DR KEGG; dsq:DICSQDRAFT_90751; -.
DR HOGENOM; CLU_007728_1_0_1; -.
DR OMA; KARRWYE; -.
DR OrthoDB; 1334586at2759; -.
DR Proteomes; UP000053319; Unassembled WGS sequence.
DR GO; GO:0016586; C:RSC-type complex; IEA:InterPro.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd04717; BAH_polybromo; 1.
DR CDD; cd04369; Bromodomain; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR037382; Rsc/polybromo.
DR PANTHER; PTHR16062:SF19; PROTEIN POLYBROMO-1; 1.
DR PANTHER; PTHR16062; SWI/SNF-RELATED; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00439; BAH; 1.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000053319}.
FT DOMAIN 26..96
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 427..552
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT REGION 115..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 752..771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 789 AA; 87799 MW; D6B33698E6D6CD09 CRC64;
MPVSAAQKTA IEEVIRAITS ASSRRAKRRL ADMFMDLVDR ESWPEYYEVI PQPRCINGVK
ANLAQNKYKN PLDAFIDLNL VFLNALHYNE DGSQIAKDAN TLKGILESEW RQRPLLPVPP
MSPAKPPSAT QKGNASKDQK ERAAVVPGPI KSQTTAASSS KSQSKAPAKP SPPIQLNSTP
SPLQTRVSQT QHSDVKKEKE TVTVKAGTPE GEPSQDMDVD IGGTPEPEVV AQDSARDGES
EEIVRQLEKG LPRWAGFADV GWTEDLTSDR MVEIVTTLSK YRDESGNRPA ASLEGIPEET
DIPDLSFTHA LSLRLVESRS RMNYYETPQA FDKEMSQLFL KARRWYDPGT EPYGNALALQ
RFYQALTSSN PPTPPYSSTT SFASLPAGPG TATPLHSVEG DAATRVTTFR VSEKDKRIVE
EVHYKGWSIR LADWLHLSNP DDPSRPIIAH VFKCFVSEET QRKGQPGVSV CWYYRPEQTW
HPTDRQFWEN EVFKTGHFAD HPLEDIIEKI AVQFTARHVR GRPRPPFWYP GWPLYVCDSR
YHDRERAFVK IKNWNSCIPE EVRKKEEFMQ IYPFERPVFP RRHPSPFLSG AKIVAPGGVL
DANANAAPGE KVEPEKPESG GAGPGTRTRT RPKRATVQKA EAEKAAASRG VSATPMQPST
SLSYQQQTQP PYVQTYPPRE DRSIVAAAGG LAVLGSNAAI EELPPETARH FDRDPETNEV
LWFAAPPVDI VHAPPPRHSL KYLAHLARKR KGQAGEHAMD VDGAPPPKRQ KMSMTVTETL
AALLQENGL
//
