ID R7TKI2_CAPTE Unreviewed; 316 AA.
AC R7TKI2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=phosphatidylserine decarboxylase {ECO:0000256|ARBA:ARBA00012243};
DE EC=4.1.1.65 {ECO:0000256|ARBA:ARBA00012243};
GN ORFNames=CAPTEDRAFT_160543 {ECO:0000313|EMBL:ELT94293.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELT94293.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELT94293.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELT94293.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP160543}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC Evidence={ECO:0000256|ARBA:ARBA00001928};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis. {ECO:0000256|ARBA:ARBA00024326}.
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DR EMBL; AMQN01012347; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB309465; ELT94293.1; -; Genomic_DNA.
DR AlphaFoldDB; R7TKI2; -.
DR STRING; 283909.R7TKI2; -.
DR EnsemblMetazoa; CapteT160543; CapteP160543; CapteG160543.
DR HOGENOM; CLU_029061_1_0_1; -.
DR OMA; WFEHGST; -.
DR UniPathway; UPA00558; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR003817; PS_Dcarbxylase.
DR InterPro; IPR033177; PSD-B.
DR NCBIfam; TIGR00163; PS_decarb; 1.
DR PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR PANTHER; PTHR10067:SF6; PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL; 1.
DR Pfam; PF02666; PS_Dcarbxylase; 1.
PE 4: Predicted;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..316
FT /note="phosphatidylserine decarboxylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008787112"
SQ SEQUENCE 316 AA; 35592 MW; 07B44E5384F9A0F6 CRC64;
MHLPVWMRSP VLRLYIWAFS CTLEEAACTD LRTYPNLGEF FRRQLKRGVR PVHTSHCMVS
PADGRILQHG VVTPKGIEQV KGVTYSLKGF LGPLDGLLPA HVPSTETVER LKRVSSLHLM
TDEAHLKPKS VDIDPLTSSD DLSYLRRLLV HPENVLHYCI IYLAPGDYHR YHSPADWTVF
ARRHFPGELY SVSPGVARWL QGLFNFNERA VYTGSWRYGF FSMTPVGATN VGSINVYFDE
DLTTNKESHE AGTYFDESFF SKNTASPGLK IHKGQAVGDF NLGSTIVLMF EAPANFRFQQ
KIGQKVKVGQ SLGTLI
//
