ID R7UIQ7_CAPTE Unreviewed; 512 AA.
AC R7UIQ7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Sorting nexin-27 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_130010 {ECO:0000313|EMBL:ELU05983.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU05983.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU05983.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU05983.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP130010}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01007613; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB301027; ELU05983.1; -; Genomic_DNA.
DR AlphaFoldDB; R7UIQ7; -.
DR STRING; 283909.R7UIQ7; -.
DR EnsemblMetazoa; CapteT130010; CapteP130010; CapteG130010.
DR HOGENOM; CLU_028138_0_0_1; -.
DR OMA; HMALKKE; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd13338; FERM-like_C_SNX27; 1.
DR CDD; cd01777; FERM_F1_SNX27; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd06886; PX_SNX27; 1.
DR Gene3D; 1.20.80.60; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR048763; SNX17-31_FERM_F1.
DR InterPro; IPR037831; SNX17/27/31-like.
DR InterPro; IPR037827; SNX27_FERM-like_dom.
DR InterPro; IPR037833; SNX27_PX.
DR InterPro; IPR037835; SNX27_RA.
DR PANTHER; PTHR12431; SORTING NEXIN 17 AND 27; 1.
DR PANTHER; PTHR12431:SF19; SORTING NEXIN-27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF21273; SNX17-27-31_F1_FERM; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 25..118
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 143..251
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 259..347
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 58023 MW; EC943EC7918A807F CRC64;
MADSEEESCS PPAGSPSEDF SGPRVVVITK TETGFGFNVR GQVNEGGQLK SINGELYAPM
QHVSAVLEGG AAQRAGIRKG DRILEVNGSN VEGSTHKQVV DLIRSGGDSL TLTVVSVPRQ
VADQWEPSEE SSGPSLVDYS EKRSLPISVP SYQTLDRFGE KYVVYNIHMA GRHLCSRRYR
EFSGLHVQLK REFSDFNFPK LPGKWPFQLS EQQLDARRRG IEQYLEKVCA VRVLADCDVM
QEFLSTHESS TNGALHGGST VELKVLLPDR NIITVSINRT ANTHQVHEAV VQKLNMDPEI
ANYFALFEIE EYNFERKLQA SELPHNLYIK NYSTATATCI SLRKWLFCLA KEIALSSQDE
QALNCFFWQA VEEVSRGQIK PADKLYELKA LQDSGKKMEY LRQVRSMDGY GEVAFPHCLC
NSRKGGHVIA IVATSNFKLQ ACKEDGTLES QVIEFEWADI EQYEVDEESF NFAYKRDGKK
ARWVKIFTNY FVYMYECFER LKTELNWEQE DG
//
