ID R7VKQ9_CAPTE Unreviewed; 509 AA.
AC R7VKQ9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE RecName: Full=Neurotransmitter-gated ion-channel ligand-binding domain-containing protein {ECO:0000259|Pfam:PF02931};
GN ORFNames=CAPTEDRAFT_226672 {ECO:0000313|EMBL:ELU16975.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU16975.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU16975.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU16975.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP226672}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01017133; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB292772; ELU16975.1; -; Genomic_DNA.
DR AlphaFoldDB; R7VKQ9; -.
DR EnsemblMetazoa; CapteT226672; CapteP226672; CapteG226672.
DR HOGENOM; CLU_535568_0_0_1; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR PANTHER; PTHR18945:SF925; PROTON-GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 96..278
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT REGION 335..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..440
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 509 AA; 58615 MW; C4BA536E86272939 CRC64;
MSIVKQRNLI RRESMSSNAS GEISFIYKED INNLPIENTY ELPASLPTAA APRAPPLRQN
ITMASNDALA DLVRALQTLG GRGGGDNYIT DQARESRSGK VPVEIRTSFV RVIDVDTCKQ
HFEAEIFLQA RWQEPALAGM SQLELDDIDL RGYWDPLLRI NNIVGDLHES KKWRKAMQTE
PGCQNPSIIF RQRARGTFVE PLELKNFPVD VQALTLKVIS DRGNKEIAFV EDSKEISCVS
TDNFTDELEW LIYEHVDTTI HNHSKAEEYY AETHGKVTMG DIIQHPSVDF KCHVARRPGY
FLWNIILVIG FMERQKMVDK DEEYYYRLLK FRERRGRRSQ QAPPTSSRVR PAPREKPKIV
YINADKQNDL SDLLPQRLKK PKKQKPMTMP PPNFPPREGE KVFTINRESE LRKATPRLPS
AKSRKTETKR PKRRGAENTT EKGYELTANK TPGRILQHEV DAYEVEVENK RTLEKKKKTQ
GRVGRTWRPK VKTPPVTFIS RGGRLYEAY
//
