ID   R7VW69_COLLI            Unreviewed;       492 AA.
AC   R7VW69;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=L-amino-acid oxidase {ECO:0000313|EMBL:EMC90054.1};
DE   Flags: Fragment;
GN   ORFNames=A306_00869 {ECO:0000313|EMBL:EMC90054.1};
OS   Columba livia (Rock dove).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX   NCBI_TaxID=8932 {ECO:0000313|EMBL:EMC90054.1};
RN   [1] {ECO:0000313|EMBL:EMC90054.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Blood {ECO:0000313|EMBL:EMC90054.1};
RX   PubMed=23371554; DOI=10.1126/science.1230422;
RA   Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA   Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA   Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT   "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL   Science 339:1063-1067(2013).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; KB376311; EMC90054.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7VW69; -.
DR   eggNOG; KOG0029; Eukaryota.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.90.660.10; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 1.10.405.10; Guanine Nucleotide Dissociation Inhibitor, domain 1; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10742:SF355; AMINE OXIDASE; 1.
DR   PANTHER; PTHR10742; FLAVIN MONOAMINE OXIDASE; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..492
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012633076"
FT   DOMAIN          53..492
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EMC90054.1"
FT   NON_TER         492
FT                   /evidence="ECO:0000313|EMBL:EMC90054.1"
SQ   SEQUENCE   492 AA;  56052 MW;  9B5EF2189133463D CRC64;
     PVLFQILLLV GLLGADEFPC FPDKDYEELL EIAKHGLKHT THPVNVVIVG AGISGLTAAK
     LLRDAGHNVT VLEMSDRVGG RIWTYRPKGH DWYAELGAMR LPPSHRIVHE FIRQFNLRVT
     PFREDNNTWY AVNRVRKRTE EVNENPDVLN YPVDPSEEGK SATQLYREAL NKAFQKFHGM
     DCKDFIKKYD SFSTKEYLIK EGNLSRGAVQ MIGDLLNEDA GFYLSFISSV WNFEIFSNDS
     FSEIVGGFDQ LPNAFHKMLP GVVRLNSAVE KIVQDKEKDE VQVFYQSVDT WAPKSITADY
     VLVTSSAKAT RHIRFVPKLS ISKTNALRSV HYASSTKIVL ACSERFWEKD GIHGGRSITD
     RPSRFIYYPN HNFSSGVGVI LASYTWNDDS EFFLPLTDDE CLDVVFQDLA YIHQVNKDHL
     LSICNQHVIQ KWQLDRHSLG AFASLTPYQF TDYSRVLFQN EGRLYFAGEH AAQPHAWIEA
     SMKSAIRAAR NI
//